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Acute liver failure due to radiographically occult infiltration of urothelial cancer

2021Artigo científico Acesso aberto
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dc.contributor.authorTosatto, Valentina
dc.contributor.authorPimentel, João Cabral
dc.contributor.authorCruz, Cristiano
dc.contributor.authorAlmeida, André
dc.contributor.authorBoattini, Matteo
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblHospital Universitario da Universidade de Sao Paulo
dc.date.accessioned2021-06-15T22:20:56Z
dc.date.available2021-06-15T22:20:56Z
dc.date.issued2021
dc.description.abstractIntroduction: Acute liver failure (ALF) due to diffuse infiltrating solid malignancy without any focal lesions on radiographic imaging is rare. Case report: A 70-year-old man was admitted due to mental confusion, abdominal pain, and ALF. Three years before, he had undergone a left nephrectomy for urothelial carcinoma followed by adjuvant chemotherapy. The abdominal computed tomography (CT) showed hepatomegaly and ascites. Ascitic fluid had transudate characteristics, with no malignant cells. Percutaneous liver biopsy (LB) showed diffuse liver infiltration of metastatic urothelial carcinoma. The patient rapidly deteriorated and died in a week due to ALF. Discussion: History of solid cancer and hepatomegaly and/or liver failure without other obvious explanation should encourage to perform LB. Conclusion: LB is warranted to avoid misdiagnosis, prolonged hospital stays, and delay in palliative care.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent650352
dc.identifier.doi10.4322/acr.2021.256
dc.identifier.issn2236-1960
dc.identifier.otherPURE: 29566868
dc.identifier.otherPURE UUID: 01797d56-d091-4182-9fbd-3c46c84c269c
dc.identifier.otherScopus: 85104879935
dc.identifier.urihttp://hdl.handle.net/10362/119309
dc.identifier.urlhttps://www.scopus.com/pages/publications/85104879935
dc.language.isoeng
dc.peerreviewedyes
dc.subjectBiopsy
dc.subjectNeoplasms
dc.subjectPalliative care
dc.subjectPathology and Forensic Medicine
dc.subjectInternal Medicine
dc.subjectSDG 3 - Good Health and Well-being
dc.titleAcute liver failure due to radiographically occult infiltration of urothelial canceren
dc.typejournal article
degois.publication.titleAutopsy and Case Reports
degois.publication.volume11
dspace.entity.typePublication
rcaap.rightsopenAccess

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