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Contribuição da curva de fluxo-volume na detecção de obstrução da via aérea central

dc.contributor.authorRaposo, Liliana B. P. A.
dc.contributor.authorBugalho, António
dc.contributor.authorGomes, Maria João Marques
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.institutionCentro de Estudos de Doenças Crónicas (CEDOC)
dc.contributor.pblSociedade Brasileira de Pneumologia e Tisiologia
dc.date.accessioned2024-10-17T22:24:48Z
dc.date.available2024-10-17T22:24:48Z
dc.date.issued2013-07-01
dc.description.abstractObjective: To assess the sensitivity and specificity of flow-volume curves in detecting central airway obstruction (CAO), and to determine whether their quantitative and qualitative criteria are associated with the location, type and degree of obstruction. Methods: Over a four-month period, we consecutively evaluated patients with bronchoscopy indicated. Over a one-week period, all patients underwent clinical evaluation, flow-volume curve, bronchoscopy, and completed a dyspnea scale. Four reviewers, blinded to quantitative and clinical data, and bronchoscopy results, classified the morphology of the curves. A fifth reviewer determined the morphological criteria, as well as the quantitative criteria. Results: We studied 82 patients, 36 (44%) of whom had CAO. The sensitivity and specificity of the flow-volume curves in detecting CAO were, respectively, 88.9% and 91.3% (quantitative criteria) and 30.6% and 93.5% (qualitative criteria). The most prevalent quantitative criteria in our sample were FEF50%/FIF50% > 1, in 83% of patients, and FEV1/PEF > 8 mL. L-1. min-1, in 36%, both being associated with the type, location, and degree of obstruction (p < 0.05). There was concordance among the reviewers as to the presence of CAO. There is a relationship between the degree of obstruction and dyspnea. Conclusions: The quantitative criteria should always be calculated for flow-volume curves in order to detect CAO, because of the low sensitivity of the qualitative criteria. Both FEF50%/FIF50% > 1 and FEV1/PEF > 8 mL. L-1. min-1 were associated with the location, type and degree of obstruction.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent8
dc.format.extent201477
dc.identifier.issn1806-3713
dc.identifier.otherPURE: 11933564
dc.identifier.otherPURE UUID: 9cdc90ae-0b2a-495d-a127-13b8346f3412
dc.identifier.otherScopus: 84884803358
dc.identifier.otherPubMed: 24068266
dc.identifier.urihttp://hdl.handle.net/10362/173665
dc.identifier.urlhttps://www.scopus.com/pages/publications/84884803358
dc.identifier.urlhttps://www.scielo.br/j/jbpneu/a/34BvRdddcYR7cQ8SsYZ9qzH/?lang=en#
dc.language.isopor
dc.peerreviewedyes
dc.subjectBronchoscopy
dc.subjectLung neoplasms
dc.subjectMaximal expiratory flow-volume curves
dc.subjectSensitivity and specificity
dc.subjectPulmonary and Respiratory Medicine
dc.titleContribuição da curva de fluxo-volume na detecção de obstrução da via aérea centralpt
dc.title.alternativeContribution of flow-volume curves to the detection of central airway obstructionen
dc.typejournal article
degois.publication.firstPage447
degois.publication.issue4
degois.publication.lastPage454
degois.publication.titleJornal Brasileiro de Pneumologia
degois.publication.volume39
dspace.entity.typePublication
rcaap.rightsopenAccess

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