Publicação
The roles of tubulin post-translational modifications in cancer
| datacite.subject.fos | Ciências Naturais | pt_PT |
| dc.contributor.advisor | Maiato, Helder José Martins | |
| dc.contributor.advisor | Bettencourt-Dias, Mónica | |
| dc.contributor.author | Lopes, Danilo | |
| dc.date.accessioned | 2023-03-13T19:59:23Z | |
| dc.date.available | 2023-03-13T19:59:23Z | |
| dc.date.issued | 2023-02-22 | |
| dc.date.submitted | 2023-02 | |
| dc.description.abstract | "Microtubules are dynamic structures of the cytoskeleton composed by several α/β-tubulin isotypes that may undergo various post-translational modifications (PTMs). This “tubulin code” generates microtubule diversity that modulates key cellular functions. However, whether and how these tubulin PTMs regulate cancer cell properties remains largely unknown. Here, we proposed to understand: (1) the regulation of tubulin PTMs in cancer; (2) the functional implications of the “cancer tubulin code”. | pt_PT |
| dc.identifier.tid | 101762275 | |
| dc.identifier.uri | http://hdl.handle.net/10362/150442 | |
| dc.language.iso | eng | pt_PT |
| dc.relation | The role of Tubulin Post-Translational Modifications in Human Cancers and During Aging | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | tubulin code | pt_PT |
| dc.subject | acetylation | pt_PT |
| dc.title | The roles of tubulin post-translational modifications in cancer | pt_PT |
| dc.type | doctoral thesis | |
| dspace.entity.type | Publication | |
| oaire.awardNumber | SFRH/BD/135077/2017 | |
| oaire.awardTitle | The role of Tubulin Post-Translational Modifications in Human Cancers and During Aging | |
| oaire.awardURI | info:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F135077%2F2017/PT | |
| person.familyName | da Silva Lopes | |
| person.givenName | Danilo | |
| person.identifier.ciencia-id | BF18-7709-10AA | |
| person.identifier.orcid | 0000-0003-2741-1822 | |
| project.funder.identifier | http://doi.org/10.13039/501100001871 | |
| project.funder.name | Fundação para a Ciência e a Tecnologia | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | doctoralThesis | pt_PT |
| relation.isAuthorOfPublication | c7d7f9fb-4e24-49fa-9dae-cce3bb6c2049 | |
| relation.isAuthorOfPublication.latestForDiscovery | c7d7f9fb-4e24-49fa-9dae-cce3bb6c2049 | |
| relation.isProjectOfPublication | d6027676-894b-4f5b-91bd-4548c2e6be35 | |
| relation.isProjectOfPublication.latestForDiscovery | d6027676-894b-4f5b-91bd-4548c2e6be35 | |
| thesis.degree.name | Dissertation presented to obtain the Ph.D degree in Molecular Biosciences | pt_PT |
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