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Love me or Leave me
| Nome: | Descrição: | Tamanho: | Formato: | |
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| 24.73 MB | Adobe PDF |
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Resumo(s)
"Internal state-dependent behavioral flexibility, such as the ability to switch between sexual
acceptance and rejection across the reproductive cycle, is essential for reproductive success and
social interactions. Female sexual behavior is orchestrated by hormonal and neuronal mechanisms
that integrate external stimuli with the reproductive cycle, influencing the copulatory behavior.
These mechanisms synchronize behavioral receptivity with reproductive capacity, ensuring that
copulation occurs during optimal reproductive windows, while actively suppressing sexual
behavior outside fertile periods. A key brain region in this process is the ventrolateral part of the
ventromedial hypothalamus (VMHvl), which contains hormone receptor-expressing neurons,
including those expressing the progesterone receptor (VMHvlPR+). While the VMHvl has long
been associated with female sexual receptivity, recent evidence highlights its cellular,
transcriptomic and functional heterogeneity.(...)"
Descrição
Palavras-chave
Sexual behavior Periaqueductal gray (PAG) mice Ventromedial hypothalamus (VMHv1)