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Manipulation of host cell functions by Salmonella: the role of the bacterial effector protein SteA
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Salmonella enterica serovars are Gram-negative facultative intracellular
bacterial pathogens that infect a wide variety of animals. Salmonella
infections are common in humans, causing usually typhoid fever and
gastrointestinal diseases. Salmonella enterica serovar Typhimurium (S.
Typhimurium), which is a leading cause of human gastroenteritis, has been
extensively used to study the molecular pathogenesis of Salmonella,
because of the availability of sophisticated genetic tools, and of suitable
animal and tissue culture models mimicking different aspects of Salmonella
infections.(...)