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Selective Activity of an Anthocyanin-Rich, Purified Blueberry Extract upon Pathogenic and Probiotic Bacteria

dc.contributor.authorSilva, Sara
dc.contributor.authorCosta, Eduardo M.
dc.contributor.authorMachado, Manuela
dc.contributor.authorMorais, Rui M.
dc.contributor.authorCalhau, Conceição
dc.contributor.authorCalhau, Conceição
dc.contributor.authorPintado, Manuela
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblMDPI - Multidisciplinary Digital Publishing Institute
dc.date.accessioned2023-03-15T22:35:16Z
dc.date.available2023-03-15T22:35:16Z
dc.date.issued2023-02
dc.descriptionFunding Information: This research was funded by Fundação para a Ciência e Tecnologia grant number UIDB/50016/2020 and S.Silva’s PhD fellowship SFRH/BD/90867/2012. Publisher Copyright: © 2023 by the authors.
dc.description.abstractBlueberry extracts have been widely recognized as possessing antimicrobial activity against several potential pathogens. However, the contextualization of the interaction of these extracts with beneficial bacteria (i.e., probiotics), particularly when considering the food applications of these products, may be of importance, not only because their presence is important in the regular gut microbiota, but also because they are important constituents of regular and functional foodstuffs. Therefore, the present work first sought to demonstrate the inhibitory effect of a blueberry extract upon four potential food pathogens and, after identifying the active concentrations, evaluated their impact upon the growth and metabolic activity (organic acid production and sugar consumption) of five potential probiotic microorganisms. Results showed that the extract, at a concentration that inhibited L. monocytogenes, B. cereus, E. coli and S. enteritidis (1000 μg mL−1), had no inhibitory effect on the growth of the potential probiotic stains used. However, the results demonstrated, for the first time, that the extract had a significant impact on the metabolic activity of all probiotic strains, resulting in higher amounts of organic acid production (acetic, citric and lactic acids) and an earlier production of propionic acid.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent2967628
dc.identifier.doi10.3390/foods12040734
dc.identifier.issn2304-8158
dc.identifier.otherPURE: 55930457
dc.identifier.otherPURE UUID: 2d84f4f4-f132-4e25-9872-e69d19cc2f09
dc.identifier.otherScopus: 85148905277
dc.identifier.otherPubMed: 36832808
dc.identifier.otherPubMedCentral: PMC9955905
dc.identifier.urihttp://hdl.handle.net/10362/150652
dc.identifier.urlhttps://www.scopus.com/pages/publications/85148905277
dc.language.isoeng
dc.peerreviewedyes
dc.subjectantimicrobial activity
dc.subjectblueberry extract
dc.subjectorganic acids
dc.subjectpathogen
dc.subjectprobiotic
dc.subjectshort-chain fatty acids
dc.subjectFood Science
dc.subjectMicrobiology
dc.subjectHealth(social science)
dc.subjectHealth Professions (miscellaneous)
dc.subjectPlant Science
dc.titleSelective Activity of an Anthocyanin-Rich, Purified Blueberry Extract upon Pathogenic and Probiotic Bacteriaen
dc.typejournal article
degois.publication.issue4
degois.publication.titleFoods
degois.publication.volume12
dspace.entity.typePublication
person.familyNameCalhau
person.givenNameConceição
person.identifier.ciencia-id2110-0420-1717
person.identifier.orcid0000-0001-9567-3379
person.identifier.scopus-author-id6701578877
rcaap.rightsopenAccess
relation.isAuthorOfPublication32b016c8-810a-40be-b9ee-ddfb07668a78
relation.isAuthorOfPublication.latestForDiscovery32b016c8-810a-40be-b9ee-ddfb07668a78

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