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Cervical spine involvement as initial manifestation of rheumatoid arthritis: a case report

2015-01Artigo científico Acesso aberto
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dc.contributor.authorAraújo, Filipe
dc.contributor.authorSilva, Inês
dc.contributor.authorSepriano, Alexandre
dc.contributor.authorSepriano, Alexandre
dc.contributor.authorReizinho, Carla
dc.contributor.authorMarques, Luís
dc.contributor.authorNero, Patrícia
dc.contributor.authorBranco, Jaime
dc.contributor.authorBranco, Jaime
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.institutionCentro de Estudos de Doenças Crónicas (CEDOC)
dc.contributor.pblSociedade Portuguesa de Reumatologia
dc.date.accessioned2017-07-14T22:01:14Z
dc.date.available2017-07-14T22:01:14Z
dc.date.issued2015-01
dc.description.abstractRheumatoid arthritis' synovitis affects mostly small hand and feet joints, although it may compromise any joint with a synovial lining. Cervical involvement occurs usually in longstanding disease in over half of these patients. We report the case of a 35-year old male patient who was referred to our outpatient clinic for a 2-year severe and disabling inflammatory neck pain, with incomplete response to intramuscular non-steroidal anti-inflammatory drugs and unremarkable cervical imaging studies. He also mentioned self-limited episodes of symmetric polyarthralgia involving hands, wrists, elbows, knees and feet, which started after his cervical complaints. On laboratorial workup, positive rheurriatoid factor and anti-citrullinated peptide antibody and negative HLA-B27 were found. Cervical spine magnetic resonance imaging revealed atlantoaxial subluxation and odontoid process inflammatory pannus and erosions. Rheumatoid arthritis with cervical spine involvement as initial manifestation of disease was the definite diagnosis. The patient was started on methotrexate and prednisone and he was referred to neurosurgery outpatient clinic for cervical spine fixation.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent202254
dc.identifier.issn0303-464X
dc.identifier.otherPURE: 484799
dc.identifier.otherPURE UUID: b12dff1b-ea35-4fcd-b785-f0addb4ddfb4
dc.identifier.otherresearchoutputwizard: 51470
dc.identifier.otherPubMed: 24861079
dc.identifier.otherWOS: 000354149300008
dc.identifier.otherScopus: 84930146097
dc.identifier.urihttps://research.unl.pt/admin/files/484802/925_cervical_spine_involvement_as_initial_manifestation_of_rheumatoid_arthritis_a_case_report_file.pdf
dc.identifier.urlhttps://research.unl.pt/admin/files/484802/925_cervical_spine_involvement_as_initial_manifestation_of_rheumatoid_arthritis_a_case_report_file.pdf
dc.language.isoeng
dc.peerreviewedyes
dc.subjectCervical spine
dc.subjectAtlantoaxial subluxation
dc.subjectRheumatoid arthritis
dc.subjectInflammatory pannus
dc.subjectATLANTO-AXIAL SUBLUXATION
dc.subjectMYELOPATHY
dc.subjectRheumatoid arthritis
dc.subjectCervical spine
dc.subjectInflammatory pannus
dc.subjectAtlantoaxial subluxation
dc.titleCervical spine involvement as initial manifestation of rheumatoid arthritis: a case reporten
dc.typejournal article
degois.publication.firstPage64
degois.publication.issue1
degois.publication.lastPage67
degois.publication.titleActa Reumatológica Portuguesa
degois.publication.volume40
dspace.entity.typePublication
person.familyNameSepriano
person.familyNameBranco
person.givenNameAlexandre
person.givenNameJaime
person.identifier397398
person.identifier.ciencia-id5E1B-9976-5CE4
person.identifier.ciencia-idB612-E5C3-60DC
person.identifier.orcid0000-0003-1954-0229
person.identifier.orcid0000-0001-7024-4375
person.identifier.scopus-author-id55266526300
person.identifier.scopus-author-id8417815400
rcaap.rightsopenAccess
relation.isAuthorOfPublicationd87df0c7-841b-4648-a99e-296348e2e286
relation.isAuthorOfPublication4caea9f3-40dd-4c95-98ec-0120509287c0
relation.isAuthorOfPublication.latestForDiscovery4caea9f3-40dd-4c95-98ec-0120509287c0

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