Logo do repositório
 
Publicação

Predictors of successful pulmonary valve-sparing repair in pediatric humanitarian patients with Tetralogy of Fallot

2025-12Artigo científico Acesso aberto
Ver registo simples
dc.contributor.authorMendes, Vitor
dc.contributor.authorMouloudi, Abdelkhalek
dc.contributor.authorJolou, Jalal
dc.contributor.authorNalecz, Tomasz
dc.contributor.authorAbecasis, Ana
dc.contributor.authorPereira, Telmo S.
dc.contributor.authorSologashvili, Tornike
dc.contributor.institutionGlobal Health and Tropical Medicine (GHTM)
dc.contributor.institutionInstituto de Higiene e Medicina Tropical (IHMT)
dc.contributor.institutionTB, HIV and opportunistic diseases and pathogens (THOP)
dc.contributor.pblBioMed Central (BMC)
dc.date.accessioned2025-07-31T21:20:50Z
dc.date.available2025-07-31T21:20:50Z
dc.date.issued2025-12
dc.descriptionFunding Information: Open access funding provided by University of Geneva. Publisher Copyright: © The Author(s) 2025.
dc.description.abstractIntroduction: The optimal surgical approach for right ventricular outflow tract obstruction in Tetralogy of Fallot aims to preserve the native pulmonary valve annulus, as this is associated with better long-term outcomes. Pediatric humanitarian patients often present with a delayed diagnosis and lack access to preoperative palliative treatments, reducing the likelihood of pulmonary valve annulus preservation and potentially compromising long-term outcomes. This study aims to identify independent predictors of successful pulmonary valve-sparing repair in pediatric humanitarian patients undergoing corrective surgery for Tetralogy of Fallot. Methods: Between January 2019 and May 2023, pediatric humanitarian patients with Tetralogy of Fallot underwent surgical correction at our center. We performed a comparative analysis of preoperative, intraoperative, and postoperative variables, followed by univariate and multivariate logistic regression to identify independent predictors of pulmonary valve-sparing repair. Results: A lower body mass index (OR = 0.711; p = 0.021; 95% CI = 0.533–0.949), a larger pulmonary valve annulus measured in centimeters (OR = 28.653; p = 0.008; 95% CI = 2.360-347.890) and a higher Z-score of pulmonary valve annulus (OR = 1.606; p = 0.023; 95% CI = 1.067–2.418) were identified as independent predictors of pulmonary valve-sparing repair. Conclusion: Successful pulmonary valve-sparing repair was associated with lower BMI and a larger pulmonary valve annulus (both measurements in centimeters and Z-score). These findings may help guide clinical and policy strategies to promote more equitable and effective surgical care in resource-limited settings.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent1264171
dc.identifier.doi10.1186/s13019-025-03475-x
dc.identifier.issn1749-8090
dc.identifier.otherPURE: 123191123
dc.identifier.otherPURE UUID: a1da67d2-af72-4e2c-9f6e-b06d7b2186d5
dc.identifier.otherScopus: 105006791075
dc.identifier.otherWOS: 001498518700003
dc.identifier.otherPubMed: 40437592
dc.identifier.otherPubMedCentral: PMC12117777
dc.identifier.urihttp://hdl.handle.net/10362/185855
dc.identifier.urlhttps://www.scopus.com/pages/publications/105006791075
dc.language.isoeng
dc.peerreviewedyes
dc.subjectPediatric humanitarian patients
dc.subjectPulmonary valve-sparing repair
dc.subjectTetralogy of Fallot
dc.subjectSurgery
dc.subjectPulmonary and Respiratory Medicine
dc.subjectCardiology and Cardiovascular Medicine
dc.titlePredictors of successful pulmonary valve-sparing repair in pediatric humanitarian patients with Tetralogy of Falloten
dc.typejournal article
degois.publication.issue1
degois.publication.titleJournal of Cardiothoracic Surgery
degois.publication.volume20
dspace.entity.typePublication
rcaap.rightsopenAccess

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
s13019-025-03475-x.pdf
Tamanho:
1.21 MB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

Home collection (IHMT)