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A human biomonitoring (HBM) Global Registry Framework

2021-09Recensão Acesso aberto
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dc.contributor.authorZare Jeddi, Maryam
dc.contributor.authorVirgolino, Ana
dc.contributor.authorFantke, Peter
dc.contributor.authorHopf, Nancy B.
dc.contributor.authorGalea, Karen S.
dc.contributor.authorRemy, Sylvie
dc.contributor.authorViegas, Susana
dc.contributor.authorMustieles, Vicente
dc.contributor.authorFernandez, Mariana F.
dc.contributor.authorvon Goetz, Natalie
dc.contributor.authorVicente, Joana Lobo
dc.contributor.authorSlobodnik, Jaroslav
dc.contributor.authorRambaud, Loïc
dc.contributor.authorDenys, Sébastien
dc.contributor.authorSt-Amand, Annie
dc.contributor.authorNakayama, Shoji F.
dc.contributor.authorSantonen, Tiina
dc.contributor.authorBarouki, Robert
dc.contributor.authorPasanen-Kase, Robert
dc.contributor.authorMol, Hans G.J.
dc.contributor.authorVermeire, Theo
dc.contributor.authorJones, Kate
dc.contributor.authorSilva, Maria João
dc.contributor.authorLouro, Henriqueta
dc.contributor.authorvan der Voet, Hilko
dc.contributor.authorDuca, Radu Corneliu
dc.contributor.authorVerhagen, Hans
dc.contributor.authorCanova, Cristina
dc.contributor.authorvan Klaveren, Jacob
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorBessems, Jos
dc.contributor.institutionEscola Nacional de Saúde Pública (ENSP)
dc.contributor.institutionCentro de Investigação em Saúde Pública (CISP/PHRC)
dc.contributor.institutionComprehensive Health Research Centre (CHRC) - Pólo ENSP
dc.contributor.institutionCentre for Toxicogenomics and Human Health (ToxOmics)
dc.contributor.pblElsevier Science B.V., Amsterdam.
dc.date.accessioned2021-10-07T23:24:05Z
dc.date.available2021-10-07T23:24:05Z
dc.date.issued2021-09
dc.descriptionFunding Information: Stephanie Bopp (European Commission, DG Joint Research Centre) is acknowledged to provide valuable information regarding the IPCHEM Platform. The VITO HBM data management team is acknowledged for providing specific input. The HBM expert working group of the European Chapter of the International Society for Exposure Science (ISES Europe) is acknowledged for their great support. Publisher Copyright: © 2021
dc.description.abstractData generated by the rapidly evolving human biomonitoring (HBM) programmes are providing invaluable opportunities to support and advance regulatory risk assessment and management of chemicals in occupational and environmental health domains. However, heterogeneity across studies, in terms of design, terminology, biomarker nomenclature, and data formats, limits our capacity to compare and integrate data sets retrospectively (reuse). Registration of HBM studies is common for clinical trials; however, the study designs and resulting data collections cannot be traced easily. We argue that an HBM Global Registry Framework (HBM GRF) could be the solution to several of challenges hampering the (re)use of HBM (meta)data. The aim is to develop a global, host-independent HBM registry framework based on the use of harmonised open-access protocol templates from designing, undertaking of an HBM study to the use and possible reuse of the resulting HBM (meta)data. This framework should apply FAIR (Findable, Accessible, Interoperable and Reusable) principles as a core data management strategy to enable the (re)use of HBM (meta)data to its full potential through the data value chain. Moreover, we believe that implementation of FAIR principles is a fundamental enabler for digital transformation within environmental health. The HBM GRF would encompass internationally harmonised and agreed open access templates for HBM study protocols, structured web-based functionalities to deposit, find, and access harmonised protocols of HBM studies. Registration of HBM studies using the HBM GRF is anticipated to increase FAIRness of the resulting (meta)data. It is also considered that harmonisation of existing data sets could be performed retrospectively. As a consequence, data wrangling activities to make data ready for analysis will be minimised. In addition, this framework would enable the HBM (inter)national community to trace new HBM studies already in the planning phase and their results once finalised. The HBM GRF could also serve as a platform enhancing communication between scientists, risk assessors, and risk managers/policy makers. The planned European Partnership for the Assessment of Risk from Chemicals (PARC) work along these lines, based on the experience obtained in previous joint European initiatives. Therefore, PARC could very well bring a first demonstration of first essential functionalities within the development of the HBM GRF.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent1102569
dc.identifier.doi10.1016/j.ijheh.2021.113826
dc.identifier.issn1438-4639
dc.identifier.otherPURE: 34144213
dc.identifier.otherPURE UUID: 292daf35-fe5a-42dd-9f08-0de26337acb9
dc.identifier.otherScopus: 85115793604
dc.identifier.otherPubMed: 34583227
dc.identifier.otherWOS: 000706141000002
dc.identifier.urihttp://hdl.handle.net/10362/125760
dc.identifier.urlhttps://www.scopus.com/pages/publications/85115793604
dc.language.isoeng
dc.peerreviewedyes
dc.subjectData governance
dc.subjectData value chain
dc.subjectHarmonisation
dc.subjectHuman biomonitoring
dc.subjectRegistry
dc.subjectRegulatory risk assessment
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectSDG 3 - Good Health and Well-being
dc.titleA human biomonitoring (HBM) Global Registry Frameworken
dc.title.subtitlefurther advancement of HBM research following the FAIR principlesen
dc.typereview
degois.publication.titleInternational Journal Of Hygiene And Environmental Health
degois.publication.volume238
dspace.entity.typePublication
rcaap.rightsopenAccess

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