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Human leptospirosis in Portugal

dc.contributor.authorVieira, M L
dc.contributor.authorGama-Simões (Maria Jacinta Gama-Simões), MJ
dc.contributor.authorCollares-Pereira (Margarida Collares-Pereira), M
dc.contributor.institutionInstituto de Higiene e Medicina Tropical (IHMT)
dc.contributor.pblElsevier
dc.date.accessioned2021-05-06T22:40:15Z
dc.date.available2021-05-06T22:40:15Z
dc.date.issued2006-09-01
dc.description.abstractLeptospirosis, an under-recognized public health problem, needs to be confirmed through specific laboratory diagnosis. We describe herein a series of 4618 symptomatic patients for whom a microagglutination test (MAT) serology was available, representing a unique picture of human leptospirosis in central mainland Portugal and the Azores islands of São Miguel and Terceira, over eighteen- and twelve-year periods, respectively. The distribution of the 1024 (22%) cases identified was an average 57 cases per year, with higher frequency in males (67%). These represent the majority of leptospirosis notifications in Portugal, with a higher annual incidence rate in the islands, compared to the central mainland (11.1 and 1.7/100,000 population, respectively). Middle-aged adults (25-54 years) were most frequently infected (45%). Cases occurred mainly in December and January. Serovars from nine presumptive serogroups caused infection, with a predominance of Icterohaemorrhagiae, Pomona, and Ballum, accounting for 66% of cases. Seropositivity was associated with both anicteric and icteric leptospirosis. Several risk factors and a higher transmission risk in certain areas were emphasized. Leptospirosis was confirmed as a steadily increasing public health problem; good surveillance, communication, and laboratory support are thus necessary to reduce the impact of leptospirosis in areas at risk.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent9
dc.format.extent272390
dc.identifier.doi10.1016/j.ijid.2005.07.006
dc.identifier.issn1201-9712
dc.identifier.otherPURE: 3131050
dc.identifier.otherPURE UUID: 4b4bfec5-1bc9-494d-b3ba-6faff01668ce
dc.identifier.otherScopus: 33746926795
dc.identifier.otherORCID: /0000-0002-8586-5534/work/63724250
dc.identifier.otherPubMed: 16600656
dc.identifier.urihttp://hdl.handle.net/10362/117224
dc.identifier.urlhttps://www.scopus.com/pages/publications/33746926795
dc.identifier.urlhttps://www.ijidonline.com/article/S1201-9712(06)00002-6/fulltext
dc.language.isoeng
dc.peerreviewedyes
dc.subjectHuman leptospirosis
dc.subjectPortugal
dc.subjectPublic Health
dc.subjectSeropositivity
dc.subjectEpidemiology
dc.subjectGeneral Immunology and Microbiology
dc.subjectSDG 3 - Good Health and Well-being
dc.titleHuman leptospirosis in Portugalen
dc.title.subtitlea retrospective study of eighteen yearsen
dc.typejournal article
degois.publication.firstPage378
degois.publication.issuen.º 5
degois.publication.lastPage386
degois.publication.titleInternational Journal of Infectious Diseases
degois.publication.volumeVol. 10
dspace.entity.typePublication
rcaap.rightsopenAccess

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