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HIV infection in Portugal

2025-08-01Artigo científico Acesso aberto
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dc.contributor.authorthe Portuguese HIV Study Group
dc.contributor.authorVirgolino, Ana
dc.contributor.authorFerraz, Carolina
dc.contributor.authorNicolau, Vanessa
dc.contributor.authorCortes, Rui
dc.contributor.authorPereira, Aida
dc.contributor.authorMaltez, Fernando
dc.contributor.authorCaldas, João Paulo
dc.contributor.authorLourinho, João
dc.contributor.authorAlves, Maria
dc.contributor.authorCaetano, Inês
dc.contributor.authorTeixeira, Tiago
dc.contributor.authorCasella, Isabel
dc.contributor.authorSoeiro, Cristina
dc.contributor.authorMeseiro, Andreia
dc.contributor.authorPinho, Raquel
dc.contributor.authorRibeiro, Andreia
dc.contributor.authorSerrão, Rosário
dc.contributor.authorAntunes, Francisco
dc.contributor.institutionEscola Nacional de Saúde Pública (ENSP)
dc.contributor.institutionCentro de Investigação em Saúde Pública (CISP/PHRC)
dc.contributor.institutionComprehensive Health Research Centre (CHRC) - Pólo ENSP
dc.contributor.pblMDPI - Multidisciplinary Digital Publishing Institute
dc.date.accessioned2026-01-14T15:54:54Z
dc.date.available2026-01-14T15:54:54Z
dc.date.issued2025-08-01
dc.descriptionPublisher Copyright: © 2025 by the authors.
dc.description.abstractBackground/Objectives: The timely initiation of antiretroviral therapy (ART) in persons living with HIV (PLWH) can improve clinical outcomes. However, ART commencement is often delayed. Portugal, despite having one of the highest new HIV diagnosis rates within the European Union, has limited available national-level data. Prior evidence from 2017 to 2018 suggests that the average time to ART initiation exceeds the recommendations for optimal patient benefits. This study aimed to determine the number of days from the first hospital appointment to the commencement of ART among newly diagnosed PLWH in Portugal between 2017 and 2022 at the national level and across different hospitals. It was hypothesized that newly diagnosed PLWH in Portugal experience a delay in ART initiation beyond the recommended timeframe. Methods: A retrospective analysis of records from Portuguese public tertiary care hospitals, which manage most HIV patients, was conducted. Descriptive statistics (measures of central tendency, dispersion, and frequency) were applied, along with association tests and a binary logistic regression model to examine factors influencing the timing of ART initiation. Results: A total of 2229 cases (out of 3434 received) from 19 hospitals were considered eligible. The median time interval between the first hospital appointment and ART initiation was 29.00 days, with a decreasing tendency between 2017 and 2022. Patients initiating therapy after 14 days had higher CD4 levels and lower viral loads compared to those starting within 14 days, with statistical significance. Conclusions: Continuous and regular monitoring of key indicators, such as the time to ART initiation, is pivotal for assessing the effectiveness of HIV treatment programs and pinpointing areas in need of improvement.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent466299
dc.identifier.doi10.3390/HEALTHCARE13151812
dc.identifier.issn2227-9032
dc.identifier.otherPURE: 148967885
dc.identifier.otherPURE UUID: fffb5235-0745-45a2-bc10-2558457b10bf
dc.identifier.otherScopus: 105019941706
dc.identifier.otherPubMed: 40805844
dc.identifier.otherPubMedCentral: PMC12346046
dc.identifier.otherWOS: 001548790600001
dc.identifier.urihttp://hdl.handle.net/10362/199052
dc.identifier.urlhttps://www.scopus.com/pages/publications/105019941706
dc.language.isoeng
dc.peerreviewedyes
dc.subjectclinical care continuum
dc.subjectpeople living with HIV
dc.subjectrapid ART initiation
dc.subjectretrospective analysis
dc.subjectLeadership and Management
dc.subjectHealth Policy
dc.subjectHealth Informatics
dc.subjectHealth Information Management
dc.subjectSDG 3 - Good Health and Well-being
dc.titleHIV infection in Portugalen
dc.title.subtitlemeasuring the time between linkage to care and antiretroviral therapy initiationen
dc.typejournal article
degois.publication.issue15
degois.publication.titleHealthcare (Switzerland)
degois.publication.volume13
dspace.entity.typePublication
rcaap.rightsopenAccess

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