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Stomach cancer elective surgery morbidity and mortality at 90-Day (Hold Study)

2026Artigo científico Acesso aberto
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dc.contributor.authorNeves-Marques, Claudia
dc.contributor.authorAbulazayem, Mohamed
dc.contributor.authorWong, Geoffrey Yuet Mun
dc.contributor.authorMaldonado, Ricardo David
dc.contributor.authorViswanath, Yirupaiahgari
dc.contributor.authorBoddy, Alex
dc.contributor.authorDonohoe, Claire
dc.contributor.authorScarano, Juan Pablo
dc.contributor.authorMartinino, Alessandro
dc.contributor.authorAamery, Amaar
dc.contributor.authorAbdulkhakimov, Nuriddin
dc.contributor.authorAbuobaida, Essam Eldien
dc.contributor.authorAday, Ulaş
dc.contributor.authorAl-Shami, Khayry
dc.contributor.authorAlhajami, Faris
dc.contributor.authorAlmeida, Ana
dc.contributor.authorAlmoshantaf, Mohammad Badr
dc.contributor.authorAhmed, Hassan
dc.contributor.authorAndrada, Martín
dc.contributor.authorAnwer, Abdul Wahid
dc.contributor.authorAwad, Ahmed K.
dc.contributor.authorBaili, Efstratia
dc.contributor.authorBaraket, Oussama
dc.contributor.authorBarbosa, José
dc.contributor.authorBaker, Cara
dc.contributor.authorBakri, Ashraf
dc.contributor.authorBoras, Zdenko
dc.contributor.authorCaiado, André
dc.contributor.authorCayirci, Can
dc.contributor.authorCalini, Giacomo
dc.contributor.authorCianci, Pasquale
dc.contributor.authorCinal, Esin
dc.contributor.authorChouliaras, Christos
dc.contributor.authorColak, Elif
dc.contributor.authorCorreia, Maria Teresa
dc.contributor.authorCosteira, Beatriz
dc.contributor.authorDavletshina, Viktoria
dc.contributor.authorD'Acapito, Fabrizio
dc.contributor.authorDonmez, Turgut
dc.contributor.authorDrozdov, Evgeniy
dc.contributor.authorErcolani, Giorgio
dc.contributor.authorErdene, Sarnai
dc.contributor.authorErginöz, Ergin
dc.contributor.authorFerreira, Samantha Rocha
dc.contributor.authorFragoso, Marta
dc.contributor.authorFramarini, Massimo
dc.contributor.authorGalandarova, Aysuna
dc.contributor.authorGenser, Laurent
dc.contributor.authorGorohov, Ilya
dc.contributor.authorGrosek, Jan
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblSpringer Science and Business Media Deutschland GmbH
dc.date.accessioned2025-12-02T21:00:37Z
dc.date.available2025-12-02T21:00:37Z
dc.date.issued2026
dc.descriptionPublisher Copyright: © 2025. The Author(s).
dc.description.abstractBACKGROUND: Data on multinational 90-day mortality and morbidity rates after surgery for gastric cancer is limited in the literature. This study aimed to understand the 90-day mortality and morbidity outcomes among patients undergoing elective gastric cancer surgery, as in the GASTRODATA Registry, and to identify associated risk factors. METHODS: We conducted an international prospective study on patients aged ≥ 18 years undergoing elective surgery for gastric cancer with curative intent from January 4 to September 30, 2022. Known metastatic disease, concurrent secondary cancers, gastrointestinal stromal tumour (GIST) and Siewert type I/II oesophagogastric junction malignancies were excluded. Univariate and multivariate logistic regression were used to identify variables associated with the 90-day outcome. RESULTS: 380 collaborators from 47 countries submitted data on 1538 patients. Median age was 65 years (IQR: 19-94), and 58.5% were males. 90-day morbidity and mortality rates were 38.2% (n = 587) and 2.9% (n = 45), respectively. Pre-operative higher Charlson Comorbidity Index, higher ASA score, pre-operative weight loss > 10%, positive specimen margin, and post-operative pathological IV staging (p value < 0.05) were significantly associated with clinically relevant complications and mortality. CONCLUSION: Elective gastric cancer surgery has a 90-day morbidity of 38.2% and a 90-day mortality of 2.9% globally. This study provided the most comprehensive international 90-day prospective data to date regarding gastric cancer surgery. Several factors associated with higher morbidity were identified, highlighting the importance of a unified language on surgical morbidity, prehabilitation, and ongoing audits to enhance patient outcomes.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent1399211
dc.identifier.doi10.1007/s00423-025-03890-7
dc.identifier.issn1435-2443
dc.identifier.otherPURE: 136236481
dc.identifier.otherPURE UUID: 00c9fa29-1577-4c68-9899-ef909ba9a646
dc.identifier.otherScopus: 105021764191
dc.identifier.otherPubMed: 41236666
dc.identifier.urihttp://hdl.handle.net/10362/191404
dc.identifier.urlhttps://www.scopus.com/pages/publications/105021764191
dc.language.isoeng
dc.peerreviewedyes
dc.subject90-Day postoperative outcomes
dc.subjectAnastomotic leaks
dc.subjectElective surgery
dc.subjectGastric cancer
dc.subjectMorbidity and mortality
dc.subjectMultinational audit
dc.subjectPatient safety
dc.subjectSurgical Complications
dc.subjectSurgery
dc.subjectSDG 3 - Good Health and Well-being
dc.titleStomach cancer elective surgery morbidity and mortality at 90-Day (Hold Study)en
dc.title.subtitlea prospective, international collaborative cohort studyen
dc.typejournal article
degois.publication.issue1
degois.publication.titleLangenbeck's Archives of Surgery
degois.publication.volume411
dspace.entity.typePublication
rcaap.rightsopenAccess

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