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Role of Yap8 and Yap1 b-ZIP transcription factors in arsenic stress
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Arsenic compounds are highly toxic substances; nevertheless they
are used in the treatment of acute promyelocytic leukaemia.
Therefore it is pressing to gain knowledge on its toxicity and
detoxification mechanisms. The cellular entry pathways have been
discovered and by transcriptome analysis it is known that arsenic
activates the transcription of genes activated by, among others,
Rpn4, Met4 and Yap1.(...)