Logo do repositório
 
Publicação

Preserving joint line orientation in TKA improves short- to mid-term outcomes

2025-10Recensão Acesso aberto
Ver registo simples
dc.contributor.authorJácome-Pacheco, Dúnio
dc.contributor.authorTorres, Tiago
dc.contributor.authorRodrigues, Gonçalo
dc.contributor.authorDiniz, Pedro
dc.contributor.authorGuerra-Pinto, Francisco
dc.contributor.authorCamacho, António
dc.contributor.authorGamelas, João
dc.contributor.authorSeil, Romain
dc.contributor.authorHirschmann, Michael T.
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblJohn Wiley and Sons Inc.
dc.date.accessioned2026-01-14T15:47:09Z
dc.date.available2026-01-14T15:47:09Z
dc.date.issued2025-10
dc.descriptionPublisher Copyright: © 2025 The Author(s). Journal of Experimental Orthopaedics published by John Wiley & Sons Ltd on behalf of European Society of Sports Traumatology, Knee Surgery and Arthroscopy.
dc.description.abstractPurpose: Joint line orientation (JLO) has been identified as a potential factor influencing clinical outcomes following total knee arthroplasty (TKA). This systematic review and meta-analysis aimed to assess whether preserving the JLO according to the individual knee phenotype is associated with improved clinical and functional outcomes. We hypothesised that joint line preserving (JLP) techniques would result in superior patient-reported outcome measures (PROMs) and better functional performance compared to non–joint line preserving (nJLP) approaches. Methods: A systematic search of Pubmed, CENTRAL, and Web of Science was conducted to identify comparative studies evaluating JLP versus nJLP in TKA. Studies reporting PROMs and other clinical indicators with a minimum follow-up of 12 months were included. Risk of bias was assessed using the RoB 2 tool for randomised trials and the ROBINS-I tool for non-randomised studies. Meta-analyses were performed for PROMs and range of motion, with subgroup analyses based on study quality. Results: Forty-three studies were included in the qualitative analysis, and 38 in the meta-analysis. The Forgotten Joint Score (MD: 7.59), Knee Function – Knee Society Score 2011 (MD: 6.48), Knee Injury and Osteoarthritis Outcome Score (MD: 2.74) and Oxford Knee Score (MD: 1.02) all showed statistically significant differences favouring JLP. Most subgroup analysis of low and low-to-moderate risk of bias studies further supported these effects. Conclusion: Joint line preservation in TKA is associated with short- to mid-term improvements in PROMs and other clinical outcomes. While the effect may vary across patient populations, these findings support the relevance of JLO in optimising functional results. A more comprehensive and standardised phenotypic approach could be key to better identifying the subgroups that benefit most from this strategy. Level of Evidence: Level III.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent3536851
dc.identifier.doi10.1002/jeo2.70458
dc.identifier.issn2197-1153
dc.identifier.otherPURE: 135053132
dc.identifier.otherPURE UUID: 5640a178-c894-4f39-b1dc-4de18a2dabc1
dc.identifier.otherScopus: 105020647501
dc.identifier.otherPubMed: 41180548
dc.identifier.otherWOS: 001605171100001
dc.identifier.urihttp://hdl.handle.net/10362/198952
dc.identifier.urlhttps://www.scopus.com/pages/publications/105020647501
dc.language.isoeng
dc.peerreviewedyes
dc.subjectjoint line preservation
dc.subjectknee function
dc.subjectpatient-reported outcome measures
dc.subjectpersonalized arthroplasty
dc.subjecttotal knee arthroplasty
dc.subjectOrthopedics and Sports Medicine
dc.titlePreserving joint line orientation in TKA improves short- to mid-term outcomesen
dc.title.subtitleA systematic review and meta-analysisen
dc.typereview
degois.publication.issue4
degois.publication.titleJournal of Experimental Orthopaedics
degois.publication.volume12
dspace.entity.typePublication
rcaap.rightsopenAccess

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
J_exp_orthop_-_2025_-_J_come_Pacheco_-_Preserving_joint_line_orientation_in_TKA_improves_short_to_mid_term_outcomes_A.pdf
Tamanho:
3.37 MB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

NMS - Artigos em revista internacional com arbitragem científica