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The contribution of cortical feedback projections to sensory representations in the mouse primary visual cortex
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Resumo(s)
"As visual information travels along the cortical hierarchy, our brain builds representations
of the outside world, which ultimately guide behavior. Areas in the cortical
hierarchy communicate through reciprocal cortical connections. While the role of feedforward
connections in visual processing is reasonably understood, the contributions of
feedback connections are less clear. The main source of feedback inputs to the mouse’s
primary visual cortex (V1) is a set of higher-order visual areas (HVAs). HVAs modulate
the activity of V1 and have been implicated in visual perception and contextual
modulations. Nevertheless, the impact of HVAs in V1 has been traditionally studied
by inhibiting their activity, rendering these studies unable to distinguish the contributions
of direct cortico-cortical feedback and indirect pathways.(...)"
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Cortex brain