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Development of technologies to support the diagnosis of infectious diseases and cancer to support the primary health care

2022-11-10Artigo científico Acesso aberto
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dc.contributor.authorFerreira, Matheus A. C.
dc.contributor.authorCarvalho, Dionísio D. A.
dc.contributor.authorCruz, Agnaldo S.
dc.contributor.authorCoutinho, Karilany D.
dc.contributor.authorOliveira, Carlos A. P.
dc.contributor.authorMorais, Antonio H. F.
dc.contributor.authorSantos, João Paulo Q.
dc.contributor.authorMayrink, Nadja N. V.
dc.contributor.authorGalvão-Lima, Leonardo J.
dc.contributor.authorSales-Moioli, Ana Isabela L.
dc.contributor.authorBarros, Daniele M. S.
dc.contributor.authorAlbuquerque, Gabriela A.
dc.contributor.authorAlves, Luca P. C. F.
dc.contributor.authorTeixeira, César A. D.
dc.contributor.authorHenriques, Jorge M. O.
dc.contributor.authorGil, Paulo
dc.contributor.authorGusmão, Cristine M. G.
dc.contributor.authorValentim, Ricardo A. M.
dc.contributor.institutionDEE - Departamento de Engenharia Electrotécnica e de Computadores
dc.contributor.pblSociedade Brasileira de Engenharia Biomédica
dc.date.accessioned2023-01-25T22:17:17Z
dc.date.available2023-01-25T22:17:17Z
dc.date.issued2022-11-10
dc.description54/2017). Publisher Copyright: © 2022, The Author(s).
dc.description.abstractPurpose: Primary Health Care (PHC) is the coordinator of health care in Brazil and needs to be strengthened in the diagnostic field to increase health care quality. Aiming to improve the diagnostic tools currently available in PHC, this work describes the process of development and validation of two point-of-care biomedical devices for screening patients with syphilis or different kinds of cancer. Methods: The development of these devices followed nine stages of action based on the requirements established by the Ministry of Health. During development, both systems followed the stages of circuit planning, software simulation to verify the components used, cost assessment for the acquisition of features, simulation in contact matrix, development of the embedded system, and planning of the printed circuit board and storage box. Results: Both devices underwent preliminary functionality tests to assess their quality. The performance tests applied on the device to diagnose syphilis performed 8,733,194 requests, with a flow of 2426 requests/second, reaching the desired parameters of robustness, integrity, durability, and stability. In addition, functioning tests on the cancer-screening device indicated the ability to detect standard fluorescence in a minimal (150 uL) sample volume. Conclusions: Together, the methodology used for developing the devices resulted in promising equipment to improve the diagnosis and meet the requirements for executing technologies for testing and triaging patients in PHC.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent9
dc.format.extent1333817
dc.identifier.doi10.1007/s42600-022-00247-7
dc.identifier.issn2446-4732
dc.identifier.otherPURE: 51546206
dc.identifier.otherPURE UUID: ee4c2071-2aad-444e-aebe-94f70b7f5ff6
dc.identifier.otherScopus: 85141707086
dc.identifier.otherORCID: /0000-0003-0937-4044/work/127354366
dc.identifier.urihttp://hdl.handle.net/10362/148176
dc.identifier.urlhttps://www.scopus.com/pages/publications/85141707086
dc.language.isoeng
dc.peerreviewedyes
dc.relationFunding Information: This work was supported by the “Syphilis No!” Project from the Brazilian Ministry of Health (Grant TED No
dc.subjectBiosensors
dc.subjectCancer
dc.subjectEmbedded system
dc.subjectPrimary health care
dc.subjectSyphilis
dc.subjectBiomedical Engineering
dc.subjectSDG 3 - Good Health and Well-being
dc.titleDevelopment of technologies to support the diagnosis of infectious diseases and cancer to support the primary health careen
dc.typejournal article
degois.publication.titleResearch on Biomedical Engineering
dspace.entity.typePublication
rcaap.rightsopenAccess

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FCT: DEE - Artigos em revista internacional com arbitragem científica