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Distúrbios respiratórios do sono na insuficiência cardíaca

dc.contributor.authorCarmo, João
dc.contributor.authorAraújo, Inês
dc.contributor.authorMarques, Filipa
dc.contributor.authorFonseca, Cândida
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblSociedade Portuguesa de Cardiologia | Elsevier
dc.date.accessioned2023-02-10T22:13:32Z
dc.date.available2023-02-10T22:13:32Z
dc.date.issued2017-11
dc.descriptionCopyright © 2017 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.
dc.description.abstractHeart failure (HF) is one of the most prevalent conditions worldwide and despite therapeutic advances, its prognosis remains poor. Among the multiple comorbidities in HF, sleep-disordered breathing (SDB) is frequent and worsens the prognosis. Preliminary observational studies suggested that treatment of SDB could modify the prognosis of HF, and the issue has gained importance in recent years. The diagnosis of SDB is expensive, slow and suboptimal, and there is thus a need for screening devices that are easier to use and validated in this population. The first-line treatment involves optimization of medical therapy for heart failure. Continuous positive airway pressure (CPAP) is used in patients who mainly suffer from obstructive sleep apnea. In patients with predominantly central sleep apnea, CPAP is not sufficient and adaptive servo-ventilation (ASV), despite promising results in observational studies, showed no benefit in patients with symptomatic HF and reduced ejection fraction in the SERVE-HF randomized trial; on the contrary, there was unexpectedly increased mortality in the ASV group compared to controls, and so ASV is contraindicated in these patients, calling into question the definition and pathogenesis of SDB and risk stratification in these patients. There are many gaps in the evidence, and so further research is needed to better understand this issue: definitions, simple screening methods, and whether and how to treat SDB in patients with HF.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent8
dc.format.extent1117500
dc.identifier.doi10.1016/j.repc.2017.06.007
dc.identifier.issn0870-2551
dc.identifier.otherPURE: 3334879
dc.identifier.otherPURE UUID: 42989389-91bc-4b58-a4ea-c0224a639414
dc.identifier.otherPubMed: 29162360
dc.identifier.otherScopus: 85034752131
dc.identifier.otherWOS: 000418008900013
dc.identifier.urihttp://hdl.handle.net/10362/149006
dc.language.isopor
dc.peerreviewedyes
dc.subjectAdaptive servo‐ventilation
dc.subjectDistúrbios respiratórios do sono
dc.subjectHeart failure
dc.subjectInsuficiência cardíaca
dc.subjectNon‐invasive ventilation
dc.subjectPrognosis
dc.subjectPrognóstico
dc.subjectServo‐ventilação adaptativa
dc.subjectSleep‐disordered breathing
dc.subjectTratamento
dc.subjectTreatment
dc.subjectVentilação não invasiva
dc.titleDistúrbios respiratórios do sono na insuficiência cardíacapt
dc.title.alternativeSleep-disordered breathing in heart failureThe state of the art after the SERVE-HF trialen
dc.title.subtitleo estado da arte depois do estudo SERVE‐HFpt
dc.typereview
degois.publication.firstPage859
degois.publication.issue11
degois.publication.lastPage867
degois.publication.titleRevista Portuguesa de Cardiologia
degois.publication.volume36
dspace.entity.typePublication
rcaap.rightsopenAccess

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