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Potassium Ferrite for Biomedical Applications

2023-05-22Artigo científico Acesso aberto
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dc.contributor.authorCarvalho, João P. F.
dc.contributor.authorVieira, Tânia
dc.contributor.authorSilva, Jorge Carvalho
dc.contributor.authorSoares, Paula I. P.
dc.contributor.authorFerreira, Nuno M.
dc.contributor.authorAmorim, Carlos O.
dc.contributor.authorTeixeira, Sílvia Soreto
dc.contributor.authorGraça, Manuel P. F.
dc.contributor.institutionDF – Departamento de Física
dc.contributor.institutionCENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)
dc.contributor.institutionDCM - Departamento de Ciência dos Materiais
dc.contributor.pblMolecular Diversity Preservation International (MDPI)
dc.date.accessioned2023-07-06T22:17:26Z
dc.date.available2023-07-06T22:17:26Z
dc.date.issued2023-05-22
dc.descriptionLA/P/0037/2020. LA/P/0006/2020. Publisher Copyright: © 2023 by the authors.
dc.description.abstractFerrites have been widely studied for their use in the biomedical area, mostly due to their magnetic properties, which gives them the potential to be used in diagnostics, drug delivery, and in treatment with magnetic hyperthermia, for example. In this work, KFeO2 particles were synthesized with a proteic sol-gel method using powdered coconut water as a precursor; this method is based on the principles of green chemistry. To improve its properties, the base powder obtained was subjected to multiple heat treatments at temperatures between 350 and 1300 °C. The samples obtained underwent structural, morphological, biocompatibility, and magnetic characterization. The results show that upon raising the heat treatment temperature, not only is the wanted phase detected, but also the secondary phases. To overcome these secondary phases, several different heat treatments were carried out. Using scanning electron microscopy, grains in the micrometric range were observed. Saturation magnetizations between 15.5 and 24.1 emu/g were observed for the samples containing KFeO2 with an applied field of 50 kOe at 300 K. From cellular compatibility (cytotoxicity) assays, for concentrations up to 5 mg/mL, only the samples treated at 350 °C were cytotoxic. However, the samples containing KFeO2, while being biocompatible, had low specific absorption rates (1.55–5.76 W/g).en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent13
dc.format.extent5508504
dc.identifier.doi10.3390/ma16103880
dc.identifier.issn1996-1944
dc.identifier.otherPURE: 65373998
dc.identifier.otherPURE UUID: 40780c23-5b9e-4d9d-a067-ca6bee9e3e31
dc.identifier.otherScopus: 85160428391
dc.identifier.otherWOS: 000996982800001
dc.identifier.otherPubMed: 37241507
dc.identifier.otherPubMedCentral: PMC10223094
dc.identifier.otherORCID: /0000-0001-9959-4272/work/151367251
dc.identifier.otherORCID: /0000-0001-8447-1886/work/151418589
dc.identifier.urihttp://hdl.handle.net/10362/154938
dc.identifier.urlhttps://www.scopus.com/pages/publications/85160428391
dc.language.isoeng
dc.peerreviewedyes
dc.relationFunding Information: info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50025%2F2020/PT
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50025%2F2020/PT
dc.relationInstitute of Nanostructures, Nanomodelling and Nanofabrication
dc.relationInstitute of Nanostructures, Nanomodelling and Nanofabrication
dc.relationCICECO-Aveiro Institute of Materials
dc.relationCICECO-Aveiro Institute of Materials
dc.relationinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50011%2F2020/PT
dc.subjectcellular viability
dc.subjectferrites
dc.subjectmagnetic measurements (VSM and SQUID)
dc.subjectsol-gel processes
dc.subjectspecific absorption rate (SAR)
dc.subjectX-ray diffraction
dc.subjectGeneral Materials Science
dc.subjectCondensed Matter Physics
dc.titlePotassium Ferrite for Biomedical Applicationsen
dc.typejournal article
degois.publication.issue10
degois.publication.titleMaterials
degois.publication.volume16
dspace.entity.typePublication
oaire.awardNumberUIDP/50025/2020
oaire.awardNumberUID/CTM/50025/2019
oaire.awardNumberUIDB/50011/2020
oaire.awardNumberUIDP/50011/2020
oaire.awardTitleInstitute of Nanostructures, Nanomodelling and Nanofabrication
oaire.awardTitleInstitute of Nanostructures, Nanomodelling and Nanofabrication
oaire.awardTitleCICECO-Aveiro Institute of Materials
oaire.awardTitleCICECO-Aveiro Institute of Materials
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50025%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FCTM%2F50025%2F2019/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50011%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50011%2F2020/PT
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream6817 - DCRRNI ID
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccess
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