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Exploring the phytochemicals of acacia melanoxylon R. Br
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Orientador(es)
Resumo(s)
Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3β-Z-coumaroyl lupeol, 3β-E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous13 C NMR assignments. Cytotoxicity of 3β-E-coumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident.
Descrição
ROTEIRO/0031/2013-PINFRA/22161/2016
Palavras-chave
Acacia melanoxylon Cytotoxicity HCT116 human colorectal cancer cells Invasive species Terpenoids Ecology, Evolution, Behavior and Systematics Ecology Plant Science SDG 3 - Good Health and Well-being SDG 15 - Life on Land