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Pericardium, epicardial adipose tissue, and heart failure with preserved ejection fraction

dc.contributor.authorTimóteo, Ana Teresa
dc.contributor.authorBarbas Albuquerque, Francisco
dc.contributor.authorLacerda Teixeira, Bárbara
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblElsevier
dc.date.accessioned2024-07-10T22:20:02Z
dc.date.available2024-07-10T22:20:02Z
dc.date.issued2024-10-01
dc.description.abstractHeart failure is an important cause of mortality and morbidity worldwide. Heart failure with preserved ejection fraction (HFpEF) incidence and prevalence is increasing, and the phenotype associated with obesity is the most frequent. Epicardial adipose tissue (EAT) is directly associated with systemic obesity and several previous studies have shown a clear link between EAT and HFpEF. Moreover, the restriction induced by the pericardium is also linked to HFpEF. In this review we will describe the epidemiological association between the pericardium, EAT and HFpEF, how to quantify EAT, what are the pathophysiological mechanism to explain theses association and how can the pericardium and EAT be a treatment target in patients with HFpEF.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent799764
dc.identifier.doi10.1016/j.ijcard.2024.132303
dc.identifier.issn0167-5273
dc.identifier.otherPURE: 94845990
dc.identifier.otherPURE UUID: 2bda5fb5-0069-43a9-8dfc-d46fcdcf3389
dc.identifier.otherScopus: 85197024617
dc.identifier.urihttp://hdl.handle.net/10362/169527
dc.identifier.urlhttps://www.scopus.com/pages/publications/85197024617
dc.language.isoeng
dc.peerreviewedyes
dc.subjectEpicardial adipose tissue
dc.subjectHeart failure with preserved ejection fraction
dc.subjectPericardium
dc.subjectCardiology and Cardiovascular Medicine
dc.subjectSDG 3 - Good Health and Well-being
dc.titlePericardium, epicardial adipose tissue, and heart failure with preserved ejection fractionen
dc.title.subtitlePathophysiology, quantification and treatment targeten
dc.typereview
degois.publication.titleInternational Journal of Cardiology
degois.publication.volume412
dspace.entity.typePublication
rcaap.rightsopenAccess

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