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Quality of life score association with other patient-reported outcomes

dc.contributor.authorMarques, Irene
dc.contributor.authorViamonte, Sofia
dc.contributor.authorSevero, Milton
dc.contributor.authorGomes Pinto, António
dc.contributor.authorFonseca, Cândida
dc.contributor.authorCarvalho, Henrique Cyrne
dc.contributor.authorFonseca, Cândida
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblSociedade Portuguesa de Cardiologia | Elsevier
dc.date.accessioned2025-09-16T21:47:34Z
dc.date.available2025-09-16T21:47:34Z
dc.date.issued2025-10
dc.descriptionPublisher Copyright: © 2025 Sociedade Portuguesa de Cardiologia
dc.description.abstractIntroduction and objectives: Pragmatic validated instruments are needed to assess quality of life (QoL) in the real-world care of heart failure (HF) patients. This study aimed to validate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) in European Portuguese and to search for associations with other patient-reported outcomes (PROs). Methods: This is a single-center prospective study with two samples of HF patients, used for MLHFQ translation, cultural adaptation and validation. Validation sample included patients managed in a multidisciplinary HF clinic between February 29, 2016, and February 29, 2020. Results: The validation sample included 294 HF patients, with a median age of 78 years, 53.1% female sex, 45.2% with reduced left ventricle ejection fraction (LVEF) and 43.9% with preserved LVEF. The principal component analysis identified three components, representing three groups of questions from the MLHFQ, each related to one domain and subscore: physical, emotional and social. The validated version showed a reliable general factor and good internal consistency. MLHFQ total score was associated with all the other variables studied. All the scores were strongly associated with NYHA functional class. Associations were found between the physical score and both the Borg fatigue score and the six-minute walking distance. Emotional score was associated with both anxiety and depression scores from Hospital Anxiety and Depression Scale. Conclusions: This study validated the MLHFQ in Portuguese and revealed the existence of three subscores. It enables the pragmatic assessment of the QoL of Portuguese HF patients, particularly of those with preserved LVEF, and future research concerning PROs.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent2262622
dc.identifier.doi10.1016/j.repc.2025.03.005
dc.identifier.issn0870-2551
dc.identifier.otherPURE: 128599451
dc.identifier.otherPURE UUID: cb0a0d6c-4e77-46c4-8119-9b1a46c7574f
dc.identifier.otherScopus: 105012519255
dc.identifier.urihttp://hdl.handle.net/10362/187972
dc.identifier.urlhttps://www.scopus.com/pages/publications/105012519255
dc.language.isoeng
dc.peerreviewedyes
dc.subjectHeart failure
dc.subjectPatient reported outcome measures
dc.subjectQuality of life
dc.subjectCardiology and Cardiovascular Medicine
dc.titleQuality of life score association with other patient-reported outcomesen
dc.title.subtitleValidating Minnesota Living with Heart Failure Questionnaire to Portugueseen
dc.typejournal article
degois.publication.firstPage607
degois.publication.issue10
degois.publication.lastPage618
degois.publication.titleRevista Portuguesa de Cardiologia
degois.publication.volume44
dspace.entity.typePublication
person.familyNameFonseca
person.givenNameCândida
person.identifier.ciencia-id6310-41B5-72DC
person.identifier.orcid0000-0003-3019-5956
person.identifier.scopus-author-id7004665987
rcaap.rightsopenAccess
relation.isAuthorOfPublication21c9d324-db15-46fc-b443-18becfd1dc7e
relation.isAuthorOfPublication.latestForDiscovery21c9d324-db15-46fc-b443-18becfd1dc7e

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