Logo do repositório
 
Publicação

Occupational exposure to Bisphenol A (BPA)

2017-09-01Recensão Acesso aberto
Ver registo simples
dc.contributor.authorRibeiro, Edna
dc.contributor.authorLadeira, Carina
dc.contributor.authorViegas , Susana
dc.contributor.institutionCentro de Investigação em Saúde Pública (CISP/PHRC)
dc.contributor.pblMDPI - Multidisciplinary Digital Publishing Institute
dc.date.accessioned2018-02-15T23:11:07Z
dc.date.available2018-02-15T23:11:07Z
dc.date.issued2017-09-01
dc.description.abstractBisphenol A (BPA), 2,2-bis(4-hydroxyphenyl) propane, is one of the most utilized industrial chemicals worldwide, with the ability to interfere with/or mimic estrogenic hormones with associated biological responses. Environmental human exposure to this endocrine disruptor, mostly through oral intake, is considered a generalized phenomenon, particularly in developed countries. However, in the context of occupational exposure, non-dietary exposure sources (e.g., air and contact) cannot be underestimated. Here, we performed a review of the literature on BPA occupational exposure and associated health effects. Relevantly, the authors only identified 19 studies from 2009 to 2017 that demonstrate that occupationally exposed individuals have significantly higher detected BPA levels than environmentally exposed populations and that the detection rate of serum BPA increases in relation to the time of exposure. However, only 12 studies performed in China have correlated potential health effects with detected BPA levels, and shown that BPA-exposed male workers are at greater risk of male sexual dysfunction across all domains of sexual function; also, endocrine disruption, alterations to epigenetic marks (DNA methylation) and epidemiological evidence have shown significant effects on the offspring of parents exposed to BPA during pregnancy. This overview raises awareness of the dramatic and consistent increase in the production and exposure of BPA and creates urgency to assess the actual exposure of workers to this xenoestrogen and to evaluate potential associated adverse health effects.en
dc.description.versionpublished
dc.format.extent305477
dc.identifier.doi10.3390/toxics5030022
dc.identifier.issn2305-6304
dc.identifier.otherPURE: 3305132
dc.identifier.otherPURE UUID: 086ed746-17f1-4b3d-a660-5a28e608b99b
dc.identifier.otherScopus: 85029520316
dc.identifier.otherWOS: 000412074100009
dc.identifier.otherPubMed: 29051454
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85029520316&partnerID=8YFLogxK
dc.identifier.urlhttps://www.scopus.com/pages/publications/85029520316
dc.language.isoeng
dc.peerreviewedyes
dc.subjectBisphenol A (BPA)
dc.subjectEndocrine disruptor
dc.subjectExposure assessment
dc.subjectGenotoxicity
dc.subjectHealth effects
dc.subjectOccupational exposure
dc.subjectToxicology
dc.subjectHealth, Toxicology and Mutagenesis
dc.subjectChemical Health and Safety
dc.subjectSDG 3 - Good Health and Well-being
dc.titleOccupational exposure to Bisphenol A (BPA)en
dc.title.subtitlea reality that still needs to be unveileden
dc.typereview
degois.publication.issue3
degois.publication.titleToxics
degois.publication.volume5
dspace.entity.typePublication
rcaap.rightsopenAccess

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura
Nome:
Ribeiro_Toxics_5_3_22.pdf
Tamanho:
298.32 KB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

Home collection (ENSP)