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Determinants of Neonatal Mortality at a Referral Paediatric Hospital in Angola

2024-11-30Artigo científico Acesso aberto
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dc.contributor.authorAvelino, Israel C.
dc.contributor.authorVan-Dúnem, Joaquim
dc.contributor.authorVarandas, Luís
dc.contributor.institutionInstituto de Higiene e Medicina Tropical (IHMT)
dc.contributor.institutionGlobal Health and Tropical Medicine (GHTM)
dc.contributor.institutionLaboratório Associado de Translacção e Inovação para a Saúde Global - LA Real (Pólo IHMT)
dc.contributor.institutionVector borne diseases and pathogens (VBD)
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblMolecular Diversity Preservation International (MDPI)
dc.date.accessioned2025-03-21T21:20:33Z
dc.date.available2025-03-21T21:20:33Z
dc.date.issued2024-11-30
dc.descriptionFunding Information: This research was partial funded by Fundação para a Ciência e Tecnologia (https://www.fct.pt/) project GHTM—UID/04413/2020 (https://ghtm.ihmt.unl.pt/).
dc.description.abstractNeonatal mortality rates in developing countries are influenced by a complex array of factors. Despite advancements in healthcare, Angola has one of the highest neonatal mortality rates in sub-Saharan Africa, with significant contributors including premature birth, intrapartum events, tetanus, and sepsis. This study, utilizing key theoretical frameworks such as intersectionality, social determinants of health (SDOH), and ecosocial theory, aimed to identify the primary causes and contributing factors of neonatal mortality among infants admitted to the Neonatology Service at DBPH in Luanda from May 2022 to June 2023. A retrospective matched case–control design was employed, pairing each neonatal death with two surviving neonates based on age and sex. The analysis included 318 newborns, of whom 106 experienced hospital deaths. A stepwise binary logistic regression model was used to examine associations between variables and neonatal mortality. Variables with p < 0.25 in bivariate analysis were included in the multivariate model. Significant factors associated with neonatal mortality included the following: a low Apgar score at 1 min (<7) (OR 2.172; 95% CI: 1.436–4.731); maternal age under 20 years (OR 3.746; 95% CI: 2.172–6.459); home delivery (OR 1.769; 95% CI: 1.034–3.027); and duration of illness before admission ≥ 3 days (OR 2.600; 95% CI: 1.317–5.200). Addressing these issues requires urgent interventions, including improving Apgar score management through enhanced training for healthcare professionals, supporting young mothers with intensified maternal education, ensuring deliveries occur in appropriate healthcare settings, and improving universal health coverage and referral systems. These measures could be crucial for enhancing neonatal care and reducing mortality.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent16
dc.format.extent856494
dc.identifier.doi10.3390/ijerph21121609
dc.identifier.issn1661-7827
dc.identifier.otherPURE: 112586241
dc.identifier.otherPURE UUID: 904cc853-c17c-42f8-86b5-c7ee014de491
dc.identifier.otherScopus: 85213407507
dc.identifier.otherPubMed: 39767450
dc.identifier.otherPubMedCentral: PMC11675793
dc.identifier.urihttp://hdl.handle.net/10362/181086
dc.identifier.urlhttps://www.scopus.com/pages/publications/85213407507
dc.language.isoeng
dc.peerreviewedyes
dc.subjectAngola
dc.subjectcase–control study
dc.subjectneonatal care
dc.subjectneonatal mortality
dc.subjectPollution
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectHealth, Toxicology and Mutagenesis
dc.subjectSDG 3 - Good Health and Well-being
dc.titleDeterminants of Neonatal Mortality at a Referral Paediatric Hospital in Angolaen
dc.title.subtitleA Case–Control Study Using Theoretical Frameworksen
dc.typejournal article
degois.publication.issue12
degois.publication.titleInternational Journal of Environmental Research and Public Health
degois.publication.volume21
dspace.entity.typePublication
rcaap.rightsopenAccess

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