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Bioactivity of chicory byproducts and their colonic metabolites in intestinal inflammation
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Resumo(s)
"Intestinal inflammation is a response to tissue injury and infection and is a central feature of Inflammatory Bowel Disease (IBD), which includes Crohn’s disease (CD) and Ulcerative Colitis (UC). These disorders arise from genetic and environmental factors, and current treatments involve pharmacological therapy and dietary interventions. Disruption of the intestinal barrier leads to increased permeability, and its dysfunction is a key hallmark of IBD. Plant-derived bioactive compounds, particularly sesquiterpene lactones (SLs) from chicory, have been investigated for their potential to modulate inflammatory responses.(...)"
Descrição
Palavras-chave
Intestinal inflammation Bowel Disease chicory roots colonic metabolites