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The atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablation

2022-12Artigo científico Acesso aberto
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dc.contributor.authorSilva Cunha, Pedro
dc.contributor.authorPortugal, Guilherme
dc.contributor.authorLaranjo, Sérgio
dc.contributor.authorAlves, Marta
dc.contributor.authorLuísa Papoila, Ana
dc.contributor.authorValente, Bruno
dc.contributor.authorSofia Delgado, Ana
dc.contributor.authorLousinha, Ana
dc.contributor.authorPaulo, Margarida
dc.contributor.authorBrás, Manuel
dc.contributor.authorGuerra, Cátia
dc.contributor.authorCruz Ferreira, Rui
dc.contributor.authorMartins Oliveira, Mário
dc.contributor.institutionComprehensive Health Research Centre (CHRC) - pólo NMS
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblElsevier BV
dc.date.accessioned2022-11-14T22:09:56Z
dc.date.available2022-11-14T22:09:56Z
dc.date.issued2022-12
dc.description.abstractObjective: This study aimed to assess whether atrial fibrillation (AF) occurrence or its corresponding daily mean burden (in minutes/day) during the mid to late blanking period after pulmonary vein isolation (PVI), predicts AF recurrence. Methods: Analysis of consecutive first PVI ablation patients undergoing prolonged electrocardiogram (ECG) monitoring during the second and third months after PVI. The clinical variables, total AF burden, and their relationship with time to recurrence were studied. Results: 477 patients with a mean age of 56.9 (SD = 12.3) years (63.7 % male; 71.7 % paroxysmal AF), from which 317 (66.5 %) had an external event recorder between 30 and 90 days after ablation. Median follow-up of 16.0 (P 25:12.0: P 75:33.0) months, 177 (37 %) patients had an AF recurrence, with 106 (22.2 %) having the first episode after 12 months of follow-up. In the group of patients with an event recorder, 80 (25.2 %) had AF documented during the blanking period. Multivariable analysis showed that AF during the blanking period was associated with a 4-fold higher risk of recurrence (HR: 3.98; 95 %CI: 2.95–5.37), and, compared to patients in sinus rhythm, those with an AF burden ≥ 23 min/day had an approximately 7-fold higher risk of recurrence (HR estimate: 6.79; 95 %CI: 4.56–10.10). Conclusions: The probability of experiencing AF recurrence can be predicted by atrial tachyarrhythmia episodes during the second and third months after PVI. Atrial arrhythmias burden > 23 min/day has a high predictive ability for recurrence.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent1197691
dc.identifier.doi10.1016/j.ijcha.2022.101138
dc.identifier.issn2352-9067
dc.identifier.otherPURE: 47607868
dc.identifier.otherPURE UUID: d42b9122-f15c-4db1-8fd3-f30d220a058c
dc.identifier.otherScopus: 85140921757
dc.identifier.otherWOS: 000876498200002
dc.identifier.urihttp://hdl.handle.net/10362/145497
dc.identifier.urlhttps://www.scopus.com/pages/publications/85140921757
dc.language.isoeng
dc.peerreviewedyes
dc.subjectArrhythmia burden
dc.subjectArrhythmia recurrence
dc.subjectAtrial fibrillation
dc.subjectBlanking period
dc.subjectCatheter ablation
dc.subjectPulmonary vein isolation
dc.subjectCardiology and Cardiovascular Medicine
dc.titleThe atrial fibrillation burden during the blanking period is predictive of time to recurrence after catheter ablationen
dc.typejournal article
degois.publication.titleIJC Heart and Vasculature
degois.publication.volume43
dspace.entity.typePublication
rcaap.rightsopenAccess

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