Publicação
Dissecting the rules underlying de novo centrosome biogenesis
| datacite.subject.fos | Cellular Biology | pt_PT |
| dc.contributor.advisor | Dias, Mónica Bettencourt | |
| dc.contributor.advisor | Telley, Ivo | |
| dc.contributor.author | Nabais, Catarina | |
| dc.date.accessioned | 2020-05-20T15:52:30Z | |
| dc.date.available | 2021-04-01T00:30:34Z | |
| dc.date.issued | 2019-03-11 | |
| dc.date.submitted | 2018-12 | |
| dc.description.abstract | "The centrosome is the main microtubule organising centre (MTOC) in animal cells, regulating cell motility and polarity during interphase and organising the mitotic spindle in mitosis. Each centrosome has two centrioles, a mother and a daughter, which are surrounded by a multi-layered protein network called pericentriolar material (PCM) (Loncarek and Bettencourt-Dias, 2018; Nigg and Holland, 2018). The PCM contains critical components that anchor and nucleate microtubules (MTs). Centriole biogenesis is a highly regulated process that occurs only once per cell-cycle in proliferating cells (Breslow and Holland, 2019).(...)" | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10362/97994 | |
| dc.language.iso | eng | pt_PT |
| dc.relation | ERC-2010-StG- 261344-CentriolStructure&Number | pt_PT |
| dc.relation | ERC-2015-CoG-683258- Birth&Death | pt_PT |
| dc.subject | centrosome | pt_PT |
| dc.subject | cell-cycle | pt_PT |
| dc.title | Dissecting the rules underlying de novo centrosome biogenesis | pt_PT |
| dc.type | doctoral thesis | |
| dspace.entity.type | Publication | |
| person.familyName | Antunes Angélico Pinto Nabais | |
| person.givenName | Catarina | |
| person.identifier.ciencia-id | 6E1E-9CAC-9462 | |
| person.identifier.orcid | 0000-0002-7817-3054 | |
| rcaap.embargofct | Artigos por publicar | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | doctoralThesis | pt_PT |
| relation.isAuthorOfPublication | e715820f-d87c-45b0-873d-6d40445f1c7b | |
| relation.isAuthorOfPublication.latestForDiscovery | e715820f-d87c-45b0-873d-6d40445f1c7b | |
| thesis.degree.name | Dissertation presented to obatin the Ph.D degree in Cellular Biology | pt_PT |
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