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Effects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apnea

2017-07Artigo científico Acesso aberto
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dc.contributor.authorFeliciano, A.
dc.contributor.authorOliveira, M.J.
dc.contributor.authorCysneiros, Ana
dc.contributor.authorMartinho, C.
dc.contributor.authorPalma dos Reis, Roberto
dc.contributor.authorPenque, Deborah
dc.contributor.authorPinto, P.
dc.contributor.authorBárbara, C.
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblElsevier Doyma
dc.date.accessioned2023-01-20T22:09:40Z
dc.date.available2023-01-20T22:09:40Z
dc.date.issued2017-07
dc.description.abstractIntroduction Obstructive sleep apnea syndrome (OSAS) is associated with cardiovascular/metabolic complications. Some analytical parameters (homocysteine, glycemic and lipidic profiles) are recognized markers of these consequences. Limited data is available on the association of these markers and OSAS's severity/response to positive airway pressure therapy (PAP). Material and methods In this prospective study we analyzed polysomnographic and analytical data of male patients admitted to sleep laboratory. The aim was to evaluate metabolic/cardiovascular markers in snorers and OSAS patients, to relate with sleep parameters and PAP response. One-hundred and three patients were included, and 73 (71%) were OSAS patients. OSAS patients were similar to snorers except for higher body mass index (BMI) and dyslipidemia. Severe OSAS patients showed higher glycemia, HbA1c, insulin, and insulin resistance, and lower HDL cholesterol in comparison to mild–moderate (p en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent10
dc.format.extent971972
dc.identifier.doi10.1016/j.rppnen.2017.02.010
dc.identifier.issn2173-5115
dc.identifier.otherPURE: 3229020
dc.identifier.otherPURE UUID: b82106b0-1375-4667-a5ea-3875ab1f3111
dc.identifier.otherRIS: urn:99D700E4558A13E8CC576729993520A2
dc.identifier.otherScopus: 85020993055
dc.identifier.otherPubMed: 28596012
dc.identifier.otherWOS: 000405642500004
dc.identifier.urihttp://hdl.handle.net/10362/147884
dc.identifier.urlhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85020993055&doi=10.1016%2fj.rppnen.2017.02.010&partnerID=40&md5=8e5112e22ece7be626e53f4190ccc887
dc.language.isoeng
dc.peerreviewedyes
dc.subjectGlucose metabolism
dc.subjectHOMA-IR
dc.subjectHomocysteine
dc.subjectLipid metabolism
dc.subjectObstructive sleep apnea
dc.subjectPAP
dc.titleEffects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apneaen
dc.typejournal article
degois.publication.firstPage193
degois.publication.issue4
degois.publication.lastPage202
degois.publication.titleRevista Portuguesa de Pneumologia
degois.publication.volume23
dspace.entity.typePublication
rcaap.rightsopenAccess

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