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Thrombus aspiration in patients with ST-elevation myocardial infarction

2018-04-24Artigo científico Acesso aberto
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dc.contributor.authorPereira, Hélder
dc.contributor.authorCaldeira, Daniel
dc.contributor.authorTeles, Rui Campante
dc.contributor.authorCosta, Marco
dc.contributor.authorda Silva, Pedro Canas
dc.contributor.authorda Gama Ribeiro, Vasco
dc.contributor.authorBrandão, Vítor
dc.contributor.authorMartins, Dinis
dc.contributor.authorMatias, Fernando
dc.contributor.authorPereira-Machado, Francisco
dc.contributor.authorBaptista, José
dc.contributor.authorAbreu, Pedro Farto e.
dc.contributor.authorSantos, Ricardo
dc.contributor.authorDrummond, António
dc.contributor.authorde Carvalho, Henrique Cyrne
dc.contributor.authorCalisto, João
dc.contributor.authorSilva, João Carlos
dc.contributor.authorPipa, João Luís
dc.contributor.authorMarques, Jorge
dc.contributor.authorSousa, Paulino
dc.contributor.authorFernandes, Renato
dc.contributor.authorFerreira, Rui Cruz
dc.contributor.authorRamos, Sousa
dc.contributor.authorOliveira, Eduardo Infante
dc.contributor.authorde Sousa Almeida, Manuel
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblBioMed Central (BMC)
dc.date.accessioned2019-02-26T23:14:04Z
dc.date.available2019-02-26T23:14:04Z
dc.date.issued2018-04-24
dc.description.abstractBackground: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. Methods: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). Conclusions: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent451045
dc.identifier.doi10.1186/s12872-018-0794-4
dc.identifier.issn1471-2261
dc.identifier.otherPURE: 11734698
dc.identifier.otherPURE UUID: 04ebfa57-cf78-42b9-9ccf-b316a35cd274
dc.identifier.otherScopus: 85046009523
dc.identifier.otherPubMed: 29699478
dc.identifier.otherWOS: 000430943000001
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85046009523&partnerID=8YFLogxK
dc.identifier.urlhttps://www.scopus.com/pages/publications/85046009523
dc.language.isoeng
dc.peerreviewedyes
dc.subjectAngioplasty
dc.subjectMortality
dc.subjectPortugal
dc.subjectPrimary PCI
dc.subjectThrombectomy
dc.subjectThrombus aspiration
dc.subjectCardiology and Cardiovascular Medicine
dc.titleThrombus aspiration in patients with ST-elevation myocardial infarctionen
dc.title.subtitleResults of a national registry of interventional cardiologyen
dc.typejournal article
degois.publication.issue1
degois.publication.titleBMC Cardiovascular Disorders
degois.publication.volume18
dspace.entity.typePublication
rcaap.rightsopenAccess

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