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Obsessive-compulsive disorder in the World Mental Health surveys

2025-07-09Artigo científico Acesso aberto
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dc.contributor.authorStein, Dan J.
dc.contributor.authorRuscio, Ayelet Meron
dc.contributor.authorAltwaijri, Yasmin
dc.contributor.authorChiu, Wai Tat
dc.contributor.authorSampson, Nancy A.
dc.contributor.authorAguilar-Gaxiola, Sergio
dc.contributor.authorAl-Hamzawi, Ali
dc.contributor.authorAlonso, Jordi
dc.contributor.authorChardoul, Stephanie
dc.contributor.authorGureje, Oye
dc.contributor.authorHu, Chiyi
dc.contributor.authorKaram, Elie G.
dc.contributor.authorMcGrath, John J.
dc.contributor.authorNavarro-Mateu, Fernando
dc.contributor.authorScott, Kate M.
dc.contributor.authorStagnaro, Juan Carlos
dc.contributor.authorTorres, Yolanda
dc.contributor.authorVladescu, Cristian
dc.contributor.authorWciórka, Jacek
dc.contributor.authorXavier, Miguel
dc.contributor.authorXavier, Miguel
dc.contributor.authorKessler, Ronald C.
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblBioMed Central (BMC)
dc.date.accessioned2025-08-01T21:21:00Z
dc.date.available2025-08-01T21:21:00Z
dc.date.issued2025-07-09
dc.descriptionPublisher Copyright: © 2025. The Author(s).
dc.description.abstractBACKGROUND: National surveys have suggested that obsessive-compulsive disorder (OCD) is a prevalent and impairing condition. However, there are few cross-national data on OCD, with data particularly scarce in low- and middle-income countries. Here we employ data from the World Mental Health surveys to characterize the onset, course, severity, and treatment of OCD across a range of countries in different geographic regions of the world. METHODS: Data came from general population surveys carried out in 10 countries (Argentina, Australia, Colombia, Iraq, Poland, People's Republic of China, Portugal, Romania, Saudi Arabia, Spain) using a consistent research protocol and interview. A total of 26,136 adults were assessed for OCD in face-to-face interviews and were included in the present analyses. We examined lifetime and 12-month prevalence as well as age of onset, persistence, severity, and treatment of DSM-IV OCD in six high-income countries (HICs) and four low- or middle-income countries (LMICs). We also investigated socio-demographic variables and temporally prior mental disorders as predictors of OCD onset, persistence, severity, and treatment. RESULTS: Across the 10 countries surveyed, OCD has a combined lifetime prevalence of 4.1%. The 12-month prevalence (3.0%) is nearly as high, suggesting a highly persistent course of illness. Age of onset is early, with more than 80% of OCD cases beginning by early adulthood. Most OCD cases in the community are mild (47.0%) or very mild (27.5%), with a smaller percentage designated as moderate (22.9%) or severe (2.7%) by the Yale-Brown Obsessive-Compulsive Scale. Only 19.8% of respondents with OCD received any mental health treatment in the past year, with treatment rates much higher in HICs (40.5%) than LMICs (7.0%). Cross-nationally, OCD commonly emerges in adolescence or early adulthood against a backdrop of earlier-occurring mental disorders. With few exceptions (e.g., prior social phobia), the socio-demographic and psychopathological risk factors for OCD onset, persistence, severity, and treatment are distinct. CONCLUSIONS: These cross-national data underscore clinical lessons regarding the importance of early diagnosis of OCD and comprehensive evaluation of comorbidity; draw attention to OCD as an undertreated disorder, particularly in LMIC contexts; and emphasize the public health significance of this often-overlooked condition.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent1
dc.format.extent1049881
dc.identifier.doi10.1186/s12916-025-04209-5
dc.identifier.issn1741-7015
dc.identifier.otherPURE: 123113968
dc.identifier.otherPURE UUID: 9c5953b9-2d90-4271-85de-27cb0ea3f2a7
dc.identifier.otherScopus: 105010975159
dc.identifier.otherPubMed: 40629326
dc.identifier.urihttp://hdl.handle.net/10362/185923
dc.identifier.urlhttps://www.scopus.com/pages/publications/105010975159
dc.language.isoeng
dc.peerreviewedyes
dc.subjectCommunity epidemiology
dc.subjectGlobal mental health
dc.subjectObsessive-compulsive disorder
dc.subjectWorld Mental Health surveys
dc.subjectGeneral Medicine
dc.subjectSDG 3 - Good Health and Well-being
dc.titleObsessive-compulsive disorder in the World Mental Health surveysen
dc.typejournal article
degois.publication.firstPage
degois.publication.issue1
degois.publication.lastPage
degois.publication.titleBMC Medicine
degois.publication.volume23
dspace.entity.typePublication
person.familyNameXavier
person.givenNameMiguel
person.identifier.ciencia-idD71F-6F62-6CFA
person.identifier.orcid0000-0003-2698-1284
person.identifier.scopus-author-id7006066808
rcaap.rightsopenAccess
relation.isAuthorOfPublication1f1ba027-e7cf-4b4a-906b-35d61c74eb90
relation.isAuthorOfPublication.latestForDiscovery1f1ba027-e7cf-4b4a-906b-35d61c74eb90

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