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On the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regression

dc.contributor.authorMilhinhos, Ana
dc.contributor.authorCosta, Pedro M.
dc.contributor.institutionInstituto de Tecnologia Química e Biológica António Xavier (ITQB)
dc.contributor.institutionDCV - Departamento de Ciências da Vida
dc.contributor.institutionUCIBIO - Applied Molecular Biosciences Unit
dc.contributor.pblFrontiers Media
dc.date.accessioned2021-03-26T23:26:00Z
dc.date.available2021-03-26T23:26:00Z
dc.date.issued2020-09-11
dc.descriptionUIDB/04378/2020 CEEC/IND/00175/2017 UIDB/04551/2020 UIBD /04046/2020 UIDP/04046/2020
dc.description.abstractPortugal is often portrayed as a relatively successful case in the control of COVID-19's March 2020 outbreak in Europe due to timely confinement measures, commonly referred to as the “lockdown”. As in other European Union member states, by late April, Portugal was preparing the phased loosening of such measures scheduled for the beginning of May. Despite a modest reduction in infection rates by that time, there was insufficient data to reliably forecast imminent scenarios. Using the South Korea data as scaffold, which became a paradigmatic case of recovery following a high number of infected people, we fitted the Portuguese data to biphasic models using non-linear regression and compared the two countries. The models, which yielded a good fit, showed that recovery would be slow, with over 50% active cases months after the lockdown. These findings acted at the time as a warning, showing that a high number of infected individuals, together with an unknown number of asymptomatic carriers, could increase the risk of a slow recovery, if not of new outbreaks. A month later, the models showed more favorable outcomes. However, shortly after, as the effects of leaving the lockdown became evident, the number of infections began rising again, leaving Portugal in a situation of inward and outward travel restrictions and baffling even the most conservative forecasts for the clearing of the pandemic.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent2387241
dc.identifier.doi10.3389/fpubh.2020.00495
dc.identifier.issn2296-2565
dc.identifier.otherPURE: 20262037
dc.identifier.otherPURE UUID: 113086e5-887b-491b-8127-fb6a26b7c0fc
dc.identifier.otherScopus: 85091567744
dc.identifier.otherPubMed: 33014981
dc.identifier.otherPubMedCentral: PMC7516009
dc.identifier.otherWOS: 000575936600001
dc.identifier.urihttp://hdl.handle.net/10362/114526
dc.identifier.urlhttps://www.scopus.com/pages/publications/85091567744
dc.language.isoeng
dc.peerreviewedyes
dc.subjectcoronavirus
dc.subjectEuropean Union
dc.subjectmodeling
dc.subjectnon-linear estimation
dc.subjectstatistical forecasting
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectSDG 3 - Good Health and Well-being
dc.titleOn the Progression of COVID-19 in Portugal: A Comparative Analysis of Active Cases Using Non-linear Regressionen
dc.typejournal article
degois.publication.titleFrontiers in public health
degois.publication.volume8
dspace.entity.typePublication
rcaap.rightsopenAccess

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