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Suberin biotech potential: from bactericidal nanoparticles to optical sensors.

datacite.subject.fosMolecular Biosciencespt_PT
dc.contributor.advisorPereira, Cristina Silva
dc.contributor.authorRodrigues, Rúben Miguel Lopes
dc.date.accessioned2021-12-06T16:12:16Z
dc.date.available2023-10-30T01:31:44Z
dc.date.issued2021-10-25
dc.date.submitted2021-10
dc.description.abstract"With the increased exposure to antibiotics and the matching selective pressure that it imposes, bacteria naturally have evolved to develop resistance to several antibiotics and, in the worst cases, multi drug resistance. This seriously affects the treatment of bacterial infections and the problem worsens when considering that the development of new antibiotic molecules is increasingly difficult and costly. Consequently, alternative antibacterial substances are being increasingly sought out, where antimicrobial lipids are being pointed as a promising solution. Fatty acids and monoglycerides are natural substances that possess antimicrobial properties, capable of destabilizing cell membranes, while causing several direct and indirect inhibitory effects, such as impairment of nutrient uptake, generation of peroxidation and auto-oxidation degradation products or direct lysis of bacterial cells and inhibition of enzyme activity. More importantly, evolution of resistant phenotypes is increasingly difficult. "pt_PT
dc.identifier.tid101727240
dc.identifier.urihttp://hdl.handle.net/10362/128745
dc.language.isoengpt_PT
dc.subjectSuberinpt_PT
dc.subjectplant biopolyesterpt_PT
dc.titleSuberin biotech potential: from bactericidal nanoparticles to optical sensors.pt_PT
dc.typedoctoral thesis
dspace.entity.typePublication
rcaap.embargofctArtigos por publicarpt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typedoctoralThesispt_PT
thesis.degree.nameDissertation presented to obtain the Ph.D degree in Molecular Biosciencespt_PT

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