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Quantitative image analysis of cells using morphodynamical models:
| Nome: | Descrição: | Tamanho: | Formato: | |
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| 2.32 MB | Adobe PDF |
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Orientador(es)
Resumo(s)
"Digitization and robotization of laboratory equipment has recently contributed to
the generation of high content of data and its metadata. While this seems like an
advantage for science's celerity, the analysis of such data became the limiting step
{ a very narrow bottleneck. Such is the case for imaging data acquisition and its
analysis. After collecting Gigabytes of images, researchers spend several orders of
magnitude of more time to determine the regions of interest (ROIs) (e.g. cell) and to
measure relevant attributes (e.g. mean
uorescence intensity). This manual curation
of data promotes another issue that is related with the reproducibility of the analysis,
e.g., the same researcher will hardly select the exact same ROIs in the same data set.
Furthermore, there is also the possibility of bias in the selection of which cells to use
in the analysis by biased determination of the ROIs.(---)"
Descrição
Palavras-chave
Sea urchin Spermatozoa image analysis cells morphodynamical