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Breath biomarkers in Non-Carcinogenic diseases

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The analysis of volatile organic compounds (VOCs) from human matrices like breath, perspiration, and urine has received increasing attention from academic and medical researchers worldwide. These biological-borne VOCs molecules have characteristics that can be directly related to physiologic and pathophysiologic metabolic processes. In this work, gathers a total of 292 analytes that have been identified as potential biomarkers for the diagnosis of various non-carcinogenic diseases. Herein we review the advances in VOCs with a focus on breath biomarkers and their potential role as minimally invasive tools to improve diagnosis prognosis and therapeutic monitoring.

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Funding Information: This work was financed by Fundação para a Ciência e Tecnologia (FCT – Portugal) through the grants UIDB/04559/2020(LIBPhys), and UIDP/04559/2020(LIBPhys) and PD/BDE/150627/2020. Funding Information: The authors would like to thank Fundação para a Ciência e Tecnologia (FCT - Portugal) for financing the grants UIDB/04559/2020(LIBPhys) and UIDP/04559/2020(LIBPhys). PCM would like to thank Fundação para a Ciência e Tecnologia (FCT - Portugal) for financing the grant PD/BDE/150627/2020 from the Doctoral NOVA I4H Program. Publisher Copyright: © 2023 The Author(s)

Palavras-chave

Biomarkers Breath Sampling Exhaled Breath Non-Carcinogenic Diseases VOCs Volatile Organic Compounds Biochemistry Clinical Biochemistry Biochemistry, medical SDG 3 - Good Health and Well-being

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