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Recomendações multidisciplinares portuguesas sobre o pedido de DXA e indicação de tratamento de prevenção das fraturas de fragilidade

2016-12Artigo científico Acesso aberto
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dc.contributor.authorMarques, Andréa
dc.contributor.authorRodrigues, Ana M.
dc.contributor.authorMaria Rodrigues, Ana
dc.contributor.authorRomeu, José Carlos
dc.contributor.authorRuano, Afonso
dc.contributor.authorBarbosa, Ana Paula
dc.contributor.authorSimões, Eugénia
dc.contributor.authorÁguas, Fernanda
dc.contributor.authorCanhão, Helena
dc.contributor.authorCanhão, Helena
dc.contributor.authorAlves, José Delgado
dc.contributor.authorAlves J, Delgado
dc.contributor.authorLucas, Raquel
dc.contributor.authorBranco, Jaime
dc.contributor.authorBranco, Jaime
dc.contributor.authorLaíns, Jorge
dc.contributor.authorMascarenhas, Mário
dc.contributor.authorSimões, Susete
dc.contributor.authorTavares, Viviana
dc.contributor.authorLourenço, Óscar
dc.contributor.authorSilva, J. A. P. da
dc.contributor.institutionCentro de Estudos de Doenças Crónicas (CEDOC)
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.date.accessioned2018-04-06T22:23:08Z
dc.date.available2018-04-06T22:23:08Z
dc.date.issued2016-12
dc.description.abstractObjective: To establish Portuguese recommendations regarding the indications for ordering bone densitometry measurement to (DXA) and for starting treatment to prevent osteoporotic fractures. Methods: A multidisciplinary panel, representing a wide range of medical specialties and patient associations related to osteoporosis, as well as national experts in this field and in health economics, met to develop recommendations based on available evidence and expert consensus. Recently obtained data on the epidemiologic, economic and quality-of-life aspects of osteoporotic fractures in Portugal were used to support decisions. Results: Ten recommendations were developed covering the issues of indications for ordering DXA measurements and whom to treat with anti-fracture medications. Thresholds for assessment and intervention are based on the cost-effectiveness analysis of interventions at different thresholds of a ten-year probability of osteoporotic fractures, calculated with the Portuguese version of FRAX® (FRAX®Port), and taking into account Portuguese epidemiologic and economic data. Limitations of FRAX® are highlighted and guidance for appropriate adjustment is provided, when possible. Conclusions: Cost-effectiveness thresholds for DXA examination and drug intervention aiming at fragility fracture prevention are provided for the Portuguese population. These are practical, based on national epidemiological and economic data, evidence-based, and supported by a multidisciplinary panel of experts and scientific societies. Implementation of these recommendations has the possibility to assure the most effective use of health resources in the prevention of osteoporotic fractures in Portugal.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent17
dc.format.extent427057
dc.identifier.issn2182-5173
dc.identifier.otherPURE: 3758548
dc.identifier.otherPURE UUID: 9f2a481c-8a96-4d0e-b03b-144c117b4bcf
dc.identifier.otherScielo: S2182-51732016000600010-prt
dc.identifier.otherScielo: 51732016000600010
dc.identifier.otherORCID: /0000-0003-1894-4870/work/67178140
dc.identifier.urihttp://www.scielo.mec.pt/scielo.php?script=sci_arttext&pid=S2182-51732016000600010&lng=pt&tlng=pt
dc.identifier.urlhttp://www.scielo.mec.pt/scielo.php?script=sci_arttext&pid=S2182-51732016000600010&lng=pt&tlng=pt
dc.language.isopor
dc.peerreviewedyes
dc.subjectRisco de Fratura
dc.subjectFRAX
dc.subjectOsteoporose
dc.subjectDMO
dc.subjectDXA
dc.subjectFraturas de Fragilidade
dc.subjectOrientações
dc.subjectRecomendações
dc.titleRecomendações multidisciplinares portuguesas sobre o pedido de DXA e indicação de tratamento de prevenção das fraturas de fragilidadept
dc.title.alternativePortuguese recommendations for ordering bone densitometry measurement and indications for treatment to prevent osteoporotic fracturesen
dc.typejournal article
degois.publication.firstPage425
degois.publication.issue6
degois.publication.lastPage441
degois.publication.titleRevista Portuguesa de Medicina Geral e Familiar
degois.publication.volume32
dspace.entity.typePublication
person.familyNameRodrigues
person.familyNameCanhão
person.familyNameDelgado Alves
person.familyNameBranco
person.givenNameAna Maria
person.givenNameHelena
person.givenNameJosé
person.givenNameJaime
person.identifier405554
person.identifier379800
person.identifier1256639
person.identifier.ciencia-idAE18-DA10-460C
person.identifier.ciencia-id5A17-C6D9-DBC8
person.identifier.ciencia-id631E-1A52-2A7C
person.identifier.ciencia-idB612-E5C3-60DC
person.identifier.orcid0000-0003-2046-8017
person.identifier.orcid0000-0003-1894-4870
person.identifier.orcid0000-0002-5216-4125
person.identifier.orcid0000-0001-7024-4375
person.identifier.ridC-9611-2018
person.identifier.scopus-author-id57189499663
person.identifier.scopus-author-id6602393492
person.identifier.scopus-author-id7102351299
person.identifier.scopus-author-id8417815400
rcaap.rightsopenAccess
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relation.isAuthorOfPublication.latestForDiscovery5aaba7f5-64a2-4d84-b026-f04a1050283a

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