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Inflammatory Myofibroblastic Tumour of the Common Bile Duct

dc.contributor.authorAlmeida E Sousa, Matilde
dc.contributor.authorCarvalho, Ana
dc.contributor.authorMega, Raquel
dc.contributor.authorBilhim, Tiago
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblBiblioteca Nacional de Portugal, Centro de Estudos Históricos, CELOM
dc.date.accessioned2023-01-11T22:15:52Z
dc.date.available2023-01-11T22:15:52Z
dc.date.issued2022-10
dc.description.abstractInflammatory myofibroblastic tumour is a rare entity of indeterminate biological potential with a reduced tendency for recurrence and metastasis. Although it can arise from multiple organs, the bile duct is a very rare site of origin. We report the case of a 75-year-old asymptomatic male with elevated gamma-glutamyl transferase [1575 U/L (12 - 64 U/L)] and alkaline phosphatase [271 U/L (40 - 150 U/L)]. Computed tomography showed a 17 mm hypervascular lesion in the confluence of the right and left hepatic ducts, with bile duct ectasia and right liver lobe atrophy. The patient was initially managed as having a Klatskin tumour and underwent right hepatectomy. Histology showed a spindle cell proliferation with an inflammatory infiltrate of lymphocytes, plasma cells and collagen-rich stroma, consistent with an inflammatory myofibroblastic tumour. He was discharged 30 days after admission, and nine months later remains asymptomatic. His liver function tests have normalized and follow-up tests are unremarkable.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent383736
dc.identifier.doi10.20344/amp.11641
dc.identifier.issn1646-0758
dc.identifier.otherPURE: 41768595
dc.identifier.otherPURE UUID: 03bb9f48-75ed-47e5-b8b2-6822973fe8cb
dc.identifier.otherPubMed: 35129430
dc.identifier.otherScopus: 85141254401
dc.identifier.otherWOS: 000931694600008
dc.identifier.urihttp://hdl.handle.net/10362/147353
dc.identifier.urlhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16976
dc.language.isoeng
dc.peerreviewedyes
dc.subjectBile Duct Neoplasms
dc.subjectHepatectomy
dc.subjectHepatic Duct
dc.subjectCommon
dc.subjectKlatskin Tumour
dc.subjectLiver Function Tests
dc.titleInflammatory Myofibroblastic Tumour of the Common Bile Ducten
dc.typejournal article
degois.publication.firstPage765
degois.publication.issue10
degois.publication.lastPage769
degois.publication.titleActa Médica Portuguesa
degois.publication.volume35
dspace.entity.typePublication
rcaap.rightsopenAccess

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