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Body Composition Evaluation and Clinical Markers of Cardiometabolic Risk in Patients with Phenylketonuria

2023-12Recensão Acesso aberto
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dc.contributor.authorLuengo-Pérez, Luis M.
dc.contributor.authorFernández-Bueso, Mercedes
dc.contributor.authorAmbrojo, Ana
dc.contributor.authorGuijarro, Marta
dc.contributor.authorFerreira, Ana Cristina
dc.contributor.authorPereira-da-Silva, Luís
dc.contributor.authorPereira-da-Silva, Luís
dc.contributor.authorMoreira-Rosário, André
dc.contributor.authorFaria, Ana
dc.contributor.authorCalhau, Conceição
dc.contributor.authorCalhau, Conceição
dc.contributor.authorDaly, Anne
dc.contributor.authorMacDonald, Anita
dc.contributor.authorRocha, Júlio César
dc.contributor.institutionComprehensive Health Research Centre (CHRC) - pólo NMS
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.institutionCentro de Investigação em Tecnologias e Serviços de Saúde (CINTESIS)
dc.contributor.pblMDPI AG
dc.date.accessioned2024-01-17T22:34:18Z
dc.date.available2024-01-17T22:34:18Z
dc.date.issued2023-12
dc.description.abstractCardiovascular diseases are the main cause of mortality worldwide. Patients with phenylketonuria (PKU) may be at increased cardiovascular risk. This review provides an overview of clinical and metabolic cardiovascular risk factors, explores the connections between body composition (including fat mass and ectopic fat) and cardiovascular risk, and examines various methods for evaluating body composition. It particularly focuses on nutritional ultrasound, given its emerging availability and practical utility in clinical settings. Possible causes of increased cardiometabolic risk in PKU are also explored, including an increased intake of carbohydrates, chronic exposure to amino acids, and characteristics of microbiota. It is important to evaluate cardiovascular risk factors and body composition in patients with PKU. We suggest systematic monitoring of body composition to develop nutritional management and hydration strategies to optimize performance within the limits of nutritional therapy.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent2188695
dc.identifier.doi10.3390/nu15245133
dc.identifier.issn1422-8599
dc.identifier.otherPURE: 81354259
dc.identifier.otherPURE UUID: aac80f92-d8be-45dc-8b83-0697b4a5754c
dc.identifier.otherScopus: 85180442291
dc.identifier.otherPubMed: 38140392
dc.identifier.urihttp://hdl.handle.net/10362/162416
dc.identifier.urlhttps://www.scopus.com/pages/publications/85180442291
dc.language.isoeng
dc.peerreviewedyes
dc.subjectanthropometry
dc.subjectbioelectrical impedance
dc.subjectbody composition
dc.subjectbody fat
dc.subjectDXA scan
dc.subjectmetabolic syndrome
dc.subjectmicrobioma
dc.subjectphenylketonuria
dc.subjectultrasound
dc.subjectvisceral fat
dc.subjectFood Science
dc.subjectNutrition and Dietetics
dc.subjectSDG 3 - Good Health and Well-being
dc.titleBody Composition Evaluation and Clinical Markers of Cardiometabolic Risk in Patients with Phenylketonuriaen
dc.typereview
degois.publication.issue24
degois.publication.titleNutrients
degois.publication.volume15
dspace.entity.typePublication
person.familyNamePereira-da-Silva
person.familyNameCalhau
person.givenNameLuís
person.givenNameConceição
person.identifier170920
person.identifier.ciencia-id001E-3D9B-A4CF
person.identifier.ciencia-id2110-0420-1717
person.identifier.orcid0000-0002-6480-1048
person.identifier.orcid0000-0001-9567-3379
person.identifier.ridA-3469-2008
person.identifier.scopus-author-id6701578877
rcaap.rightsopenAccess
relation.isAuthorOfPublication69bc8408-2804-4ca3-a938-90b72cadda88
relation.isAuthorOfPublication32b016c8-810a-40be-b9ee-ddfb07668a78
relation.isAuthorOfPublication.latestForDiscovery32b016c8-810a-40be-b9ee-ddfb07668a78

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NMS: CINTESIS - Artigos em revista internacional com arbitragem científica