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Impact of Smoking Status on Mortality in STEMI Patients Undergoing Mechanical Reperfusion for STEMI

2022-11Artigo científico Acesso aberto
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dc.contributor.authorDe Luca, Giuseppe
dc.contributor.authorAlgowhary, Magdy
dc.contributor.authorUguz, Berat
dc.contributor.authorOliveira, Dinaldo C.
dc.contributor.authorGanyukov, Vladimir
dc.contributor.authorZimbakov, Zan
dc.contributor.authorCercek, Miha
dc.contributor.authorJensen, Lisette Okkels
dc.contributor.authorLoh, Poay Huan
dc.contributor.authorCalmac, Lucian
dc.contributor.authorFerrer, Gerard Roura i.
dc.contributor.authorQuadros, Alexandre
dc.contributor.authorMilewski, Marek
dc.contributor.authorScotto D’Uccio, Fortunato
dc.contributor.authorvon Birgelen, Clemens
dc.contributor.authorVersaci, Francesco
dc.contributor.authorTen Berg, Jurrien
dc.contributor.authorCasella, Gianni
dc.contributor.authorWong Sung Lung, Aaron
dc.contributor.authorKala, Petr
dc.contributor.authorDíez Gil, José Luis
dc.contributor.authorCarrillo, Xavier
dc.contributor.authorDirksen, Maurits
dc.contributor.authorBecerra-Munoz, Victor M.
dc.contributor.authorLee, Michael Kang yin
dc.contributor.authorJuzar, Dafsah Arifa
dc.contributor.authorJoaquim, Rodrigo de Moura
dc.contributor.authorPaladino, Roberto
dc.contributor.authorMilicic, Davor
dc.contributor.authorDavlouros, Periklis
dc.contributor.authorBakraceski, Nikola
dc.contributor.authorZilio, Filippo
dc.contributor.authorDonazzan, Luca
dc.contributor.authorKraaijeveld, Adriaan
dc.contributor.authorGalasso, Gennaro
dc.contributor.authorArpad, Lux
dc.contributor.authorLucia, Marinucci
dc.contributor.authorVincenzo, Guiducci
dc.contributor.authorMenichelli, Maurizio
dc.contributor.authorScoccia, Alessandra
dc.contributor.authorYamac, Aylin Hatice
dc.contributor.authorUgur Mert, Kadir
dc.contributor.authorFlores Rios, Xacobe
dc.contributor.authorKovarnik, Tomas
dc.contributor.authorKidawa, Michal
dc.contributor.authorMoreu, Josè
dc.contributor.authorVincent, Flavien
dc.contributor.authorFabris, Enrico
dc.contributor.authorMartínez-Luengas, Iñigo Lozano
dc.contributor.authorBoccalatte, Marco
dc.contributor.authorBosa Ojeda, Francisco
dc.contributor.authorArellano-Serrano, Carlos
dc.contributor.authorCaiazzo, Gianluca
dc.contributor.authorCirrincione, Giuseppe
dc.contributor.authorKao, Hsien Li
dc.contributor.authorSanchis Forés, Juan
dc.contributor.authorVignali, Luigi
dc.contributor.authorPereira, Helder
dc.contributor.authorManzo, Stephane
dc.contributor.authorOrdoñez, Santiago
dc.contributor.authorÖzkan, Alev Arat
dc.contributor.authorScheller, Bruno
dc.contributor.authorLehtola, Heidi
dc.contributor.authorTeles, Rui
dc.contributor.authorMantis, Christos
dc.contributor.authorAntti, Ylitalo
dc.contributor.authorSilveira, João António Brum
dc.contributor.authorZoni, Rodrigo
dc.contributor.authorBessonov, Ivan
dc.contributor.authorSavonitto, Stefano
dc.contributor.authorKochiadakis, George
dc.contributor.authorAlexopulos, Dimitrios
dc.contributor.authorUribe, Carlos E.
dc.contributor.authorKanakakis, John
dc.contributor.authorFaurie, Benjamin
dc.contributor.authorGabrielli, Gabriele
dc.contributor.authorBarrios, Alejandro Gutierrez
dc.contributor.authorBachini, Juan Pablo
dc.contributor.authorRocha, Alex
dc.contributor.authorTam, Frankie Chor Cheung
dc.contributor.authorRodriguez, Alfredo
dc.contributor.authorLukito, Antonia Anna
dc.contributor.authorSaint-Joy, Veauthyelau
dc.contributor.authorPessah, Gustavo
dc.contributor.authorTuccillo, Andrea
dc.contributor.authorCortese, Giuliana
dc.contributor.authorParodi, Guido
dc.contributor.authorBouraghda, Mohamed Abed
dc.contributor.authorKedhi, Elvin
dc.contributor.authorLamelas, Pablo
dc.contributor.authorSuryapranata, Harry
dc.contributor.authorNardin, Matteo
dc.contributor.authorVerdoia, Monica
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblMDPI - Multidisciplinary Digital Publishing Institute
dc.date.accessioned2022-11-30T22:12:51Z
dc.date.available2022-11-30T22:12:51Z
dc.date.issued2022-11
dc.descriptionPublisher Copyright: © 2022 by the authors.
dc.description.abstractThe so-called “smoking paradox”, conditioning lower mortality in smokers among STEMI patients, has seldom been addressed in the settings of modern primary PCI protocols. The ISACS–STEMI COVID-19 is a large-scale retrospective multicenter registry addressing in-hospital mortality, reperfusion, and 30-day mortality among primary PCI patients in the era of the COVID-19 pandemic. Among the 16,083 STEMI patients, 6819 (42.3%) patients were active smokers, 2099 (13.1%) previous smokers, and 7165 (44.6%) non-smokers. Despite the impaired preprocedural recanalization (p < 0.001), active smokers had a significantly better postprocedural TIMI flow compared with non-smokers (p < 0.001); this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. Active smokers had a significantly lower in-hospital (p < 0.001) and 30-day (p < 0.001) mortality compared with non-smokers and previous smokers; this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. In conclusion, in our population, active smoking was significantly associated with improved epicardial recanalization and lower in-hospital and 30-day mortality compared with previous and non-smoking history.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent1150638
dc.identifier.doi10.3390/jcm11226722
dc.identifier.issn2077-0383
dc.identifier.otherPURE: 47974037
dc.identifier.otherPURE UUID: 043977d2-07a2-409e-87ea-317def53013d
dc.identifier.otherScopus: 85142347154
dc.identifier.otherPubMed: 36431198
dc.identifier.urihttp://hdl.handle.net/10362/145919
dc.identifier.urlhttps://www.scopus.com/pages/publications/85142347154
dc.language.isoeng
dc.peerreviewedyes
dc.subjectCOVID-19
dc.subjectmyocardial infarction
dc.subjectpercutaneous coronary intervention
dc.subjectsmoking paradox
dc.subjectGeneral Medicine
dc.titleImpact of Smoking Status on Mortality in STEMI Patients Undergoing Mechanical Reperfusion for STEMIen
dc.title.subtitleInsights from the ISACS–STEMI COVID-19 Registryen
dc.typejournal article
degois.publication.issue22
degois.publication.titleJournal of Clinical Medicine
degois.publication.volume11
dspace.entity.typePublication
rcaap.rightsopenAccess

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