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Espondilodiscite em idade pediátrica – uma doença rara, um diagnóstico difícil

dc.contributor.authorNisa, Madalena Meira
dc.contributor.authorSousa, Jessica
dc.contributor.authorPimenta, Joana
dc.contributor.authorAntunes, Joaquina
dc.contributor.authorGomes, Dora
dc.contributor.authorFaria, Cristina
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblEditora Universitaria da PUCRS
dc.date.accessioned2022-07-19T22:28:41Z
dc.date.available2022-07-19T22:28:41Z
dc.date.issued2022-05-16
dc.description.abstractIntroduction and objective: spondylodiscitis is an infection that affects the intervertebral disc and the contiguous vertebrae. It represents two to four % of all osteoarticular infections in pediatric age. The pathogen is identified in about half of the cases, with Staphylococcus aureus being the most frequently isolated. Recent studies show that between six months and four years, Kingella kingae has an important etiological role. The purpose of the presentation of this clinical case was to draw attention to this rare pathology whose diagnosis is difficult and requires a high level of suspicion. Clinical case description: a sixteen-month-old male, with a history of constipation, is brought multiple times to the Pediatric Emergency Department for a clinical picture with more than a month of evolution of persistent irritability, abdominal pain and refusal to walk, with progressive worsening. On the second visit to the Pediatric Emergency Department, he presented dorsolombalgia on palpation of the dorsolumbar spine and decreased lumbar lordosis, which led to the performance of analytical evaluation, urinalysis, renal and bladder ultrasound and dorsolumbar radiography, all without changes. On the third visit to the Pediatric Emergency Department, hospitalization was decided and dorsolumbar nuclear magnetic resonance and bone scintigraphy were requested, revealing spondylodiscitis in D7-D8. Analytical parameters had no changes, except for a slight increase in erythrocyte sedimentation rate. Blood cultures and remaining etiological study negatives. Intravenous therapy with cefuroxime and flucloxacillin was started with progressive improvement of pain. Upon discharge he was asymptomatic and maintained oral flucloxacillin until a total of six weeks of treatment. He was subsequently reassessed and remained asymptomatic, with a physical examination, analytical evaluation and dorsolumbar radiography without changes. Conclusions: spondylodiscitis is an identity that is difficult to diagnose, especially in children, due to its rarity, unspecific clinic, inability for children to verbalize their symptoms and late radiologic signs, requiring a high index of suspicion. The average time between the onset of symptoms and the diagnosis is three weeks to three months. Magnetic resonance imaging is the exam of choice. Blood cultures are often negative. The mainstay of treatment is antibiotic therapy for several weeks, but its choice and duration are controversial. Inappropriate treatment can lead to chronic pain, severe orthopaedic sequelae and devastating neurological complications. When timely and properly treated, most cases have a benign and self-limited clinical course.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent310505
dc.identifier.doi10.15448/1980-6108.2022.1.41086
dc.identifier.issn1806-5562
dc.identifier.otherPURE: 44980801
dc.identifier.otherPURE UUID: 40aef153-1268-4da3-8e6d-9d414fa3dabf
dc.identifier.otherScopus: 85132129357
dc.identifier.urihttp://hdl.handle.net/10362/142161
dc.identifier.urlhttps://www.scopus.com/pages/publications/85132129357
dc.language.isopor
dc.peerreviewedyes
dc.subjectosteoarticular infection
dc.subjectpediatrics
dc.subjectspondylodiscitis
dc.subjectGeneral Medicine
dc.titleEspondilodiscite em idade pediátrica – uma doença rara, um diagnóstico difícilpt
dc.title.alternativeSpondylodiscitis in pediatric age – a rare disease, a difficult diagnosisen
dc.typejournal article
degois.publication.issue1
degois.publication.titleScientia Medica
degois.publication.volume32
dspace.entity.typePublication
rcaap.rightsopenAccess

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