MYT1 FUNCTION IN NEUROGENESIS AND ITS INTERACTION WITH THE PRONEURAL TRANSCRIPTIONAL NETWORK: A GENOMICS APPROACH

Financiador

Organização

Publicações

Ascl1 and MyT1 transcriptional networks in vertebrate neurogenesis

Publication . Vasconcelos, Francisca Ferreira de; Castro, Diogo

Neurogenesis is a cell differentiation program in which neural stem cells undergo extensive and precise changes in gene expression on their way to become neurons. These changes are controlled to large extent by the activity of lineage-specific transcription factors. Of particular importance are classical proneural factors, such as Ascl1 (a.k.a. Mash1), that function as master regulators of the neurogenic program and are both required and sufficient to induce a complete program of neuronal differentiation.(...)

2015-09-28Tese de doutoramento

Acesso aberto

Ver mais

Entidade financiadora

Fundação para a Ciência e a Tecnologia

Número da atribuição

SFRH/BD/51178/2010