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Investigating a Noncanonical Role in Translation for Arabidopsis SR Proteins
Publication . Yáñez, Romana de Jesus Rosário; Duque, Paula
"Serine/arginine-rich (SR) proteins are essential splicing regulators with well- characterised nuclear functions. Emerging evidence from animal systems indicates that they also play noncanonical roles across several layers of gene expression regulation, including mRNA transcription, nuclear export, translation and decay. In Arabidopsis thaliana, a few SR proteins have been shown to shuttle between the nucleus and cytoplasm, yet the functional significance of this dynamic behaviour in plants remains largely unexplored. This thesis investigates the nucleocytoplasmic shuttling activity of four Arabidopsis SR proteins—SR34a, SR45, RSZ21, and RS40—as a prerequisite for potential cytoplasmic post-splicing functions. (...)"
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Fundação para a Ciência e a Tecnologia
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UI/BD/152253/2021
