Publication . Abreu, Raquel Patrícia de Sousa; Feldman, Jack
"Within the respiratory rhythm generator, the preB otzinger Complex
(preB otC), a speci c subset of glutamatergic neurons that expresses the
inhibitory peptide Somatostatin (SST) is critical for breathing. In rats,
these neurons constitute 10 15% of the preB otC and project extensively
to a broad range of respiratory-related regions (e.g., B otzinger Complex
(B otC) and Retrotrapezoid Nucleus/paraFacial Respiratory Group
(RTN/pFRG)). I proposed to investigate the modulatory role of these
neurons on breathing, in freely moving mice.(...)"