Combining siRNA and AAV therapy approaches to target human basal-like breast cancer: from vector development to anti-tumor efficacy evaluation.

Financiador

Organização

Publicações

Publication . Pinto, Ana Catarina Pereira; Alves, Paula; Brito, Catarina

This thesis aimed at the development of strategies that could contribute to the evaluation of the clinical potential of new anticancer therapies. The work was divided into two main sections comprising the development of a therapeutic approach to target cancer genetic vulnerabilities and the development of 3D tumor models incorporating cues from the stromal and immune microenvironments. (...)

2018-07Tese de doutoramento

Acesso aberto

Ver mais

Entidade financiadora

Fundação para a Ciência e a Tecnologia

Programa de financiamento

3599-PPCDT

Número da atribuição

PTDC/BBB-BIO/1240/2012