THE GENETIC BASIS AND ROLE OF THE ENVIRONMENT IN INTER-INDIVIDUAL VARIATION

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Effects of envirnonmental and genetic factors on transposable element activity

Publication . Marialva, Marta; Beldade, Patrícia

Heritable phenotypic variation is the raw material for evolution to occur through natural selection. It is a pervasive property of living organisms and, in order to understand evolutionary processes, we must study the factors that mediate the production of heritable phenotypic, and therefore genotypic variation. Transposable elements (TEs) are mobile DNA sequences that constitute a large proportion of most eukaryotic genomes and that can drive the production of adaptive genetic variation. There are many studies on transposon mobility, but these generally include only few environmental conditions, TEs and genetic backgrounds. As a consequence, we still know very little about the impact of genetic and environmental factors that can affect transposon dynamics in natural populations. Here, I proposed to overcome those limitations by analysing the impact of a multitude of factors on transposon mobility using Drosophila melanogaster as a model organism. (…)

2016Tese de doutoramento

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Entidade financiadora

Fundação para a Ciência e a Tecnologia

Número da atribuição

SFRH/BD/51882/2012