Soluble guanylate cyclase (sGC) is a heterodimeric heme-protein
composed of two subunits called α and β [1-5]. The most common heterodimeric
form is the combination of α1 with β1 subunits [1]. The α1 (80KDa) and β1 (70
KDa) subunits are 690 and 619 amino acids in length respectively, and are
encoded by the genes, GUCY1A2 and GUCY1A3 respectively [3].(...)