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Inheritance of histone H3 variants across mitotic cell divisions
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| 7.58 MB | Adobe PDF |
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Resumo(s)
Cell proliferation and differentiation into distinct cell types
during development requires the preservation of cellular phenotypes
during cell divisions. How the cell maintains its identity and how cells
with the same genetic information display different heritable
phenotypes or gene expression profiles are fundamental questions in
biology. The mitotic and/or meiotic inheritance of changes in gene
expression that are not due to changes in DNA sequences is known as
epigenetic inheritance.(...)
Descrição
Dissertation presented to obtain the Ph.D degree in Molecular Biology.
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Editora
Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica.