Utilize este identificador para referenciar este registo: http://hdl.handle.net/10362/98059
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Campo DCValorIdioma
dc.contributor.advisorAlves, Paula Marques-
dc.contributor.advisorSerra, Maria Margarida-
dc.contributor.advisorAlves, Patrícia Gomes-
dc.contributor.authorSebastião, Maria-
dc.date.accessioned2020-05-21T15:56:16Z-
dc.date.available2020-05-21T15:56:16Z-
dc.date.issued2018-09-19-
dc.date.submitted2018-09-
dc.identifier.urihttp://hdl.handle.net/10362/98059-
dc.description.abstract"Acute Myocardial Infarction (AMI) remains a leading cause of death worldwide. After AMI, clinical restauration of blood flow aggravates tissue damage (Ischemia/Reperfusion, I/R injury), critically decreasing the number of viable cardiomyocytes (CMs). Besides CMs, other myocardial cell populations such as cardiac stem/progenitor cells (CSCs) and cardiac fibroblasts (CFs) play key roles in tissue pathology and regeneration upon AMI. Several studies have demonstrated the relevant role of endogenous CSCs in myocardial repair after I/R injury, supported by the establishment of a paracrine cross talk between CSCs and the injured tissue(...)".pt_PT
dc.language.isoengpt_PT
dc.relationSFRH/BD/52339/2013pt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04462%2F2013/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/5665-PICT/MITP-TB%2FECE%2F0013%2F2013/PTpt_PT
dc.relationinfo:eu-repo/grantAgreement/FCT/9471 - RIDTI/SAICTPAC%2F0047%2F2015/PTpt_PT
dc.rightsopenAccesspt_PT
dc.subjectmyocardialpt_PT
dc.subjecthuman cardiac cellpt_PT
dc.titleTowards novel stem cell and protein based therapies for myocardium regenerationpt_PT
dc.title.alternativeExploiting myocardial ischemia/reperfusion models and advanced proteomicpt_PT
dc.typedoctoralThesispt_PT
thesis.degree.nameDissertation presented to obtain the Ph.D degree in Sciences of Engineering and Technologypt_PT
dc.subject.fosBiological Engineeringpt_PT
Aparece nas colecções:ITQB: CBL - PhD Theses

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