Utilize este identificador para referenciar este registo:
http://hdl.handle.net/10362/98059Registo completo
| Campo DC | Valor | Idioma |
|---|---|---|
| dc.contributor.advisor | Alves, Paula Marques | - |
| dc.contributor.advisor | Serra, Maria Margarida | - |
| dc.contributor.advisor | Alves, Patrícia Gomes | - |
| dc.contributor.author | Sebastião, Maria | - |
| dc.date.accessioned | 2020-05-21T15:56:16Z | - |
| dc.date.available | 2020-05-21T15:56:16Z | - |
| dc.date.issued | 2018-09-19 | - |
| dc.date.submitted | 2018-09 | - |
| dc.identifier.uri | http://hdl.handle.net/10362/98059 | - |
| dc.description.abstract | "Acute Myocardial Infarction (AMI) remains a leading cause of death worldwide. After AMI, clinical restauration of blood flow aggravates tissue damage (Ischemia/Reperfusion, I/R injury), critically decreasing the number of viable cardiomyocytes (CMs). Besides CMs, other myocardial cell populations such as cardiac stem/progenitor cells (CSCs) and cardiac fibroblasts (CFs) play key roles in tissue pathology and regeneration upon AMI. Several studies have demonstrated the relevant role of endogenous CSCs in myocardial repair after I/R injury, supported by the establishment of a paracrine cross talk between CSCs and the injured tissue(...)". | pt_PT |
| dc.language.iso | eng | pt_PT |
| dc.relation | SFRH/BD/52339/2013 | pt_PT |
| dc.relation | info:eu-repo/grantAgreement/FCT/5876/UID%2FMulti%2F04462%2F2013/PT | pt_PT |
| dc.relation | info:eu-repo/grantAgreement/FCT/5665-PICT/MITP-TB%2FECE%2F0013%2F2013/PT | pt_PT |
| dc.relation | info:eu-repo/grantAgreement/FCT/9471 - RIDTI/SAICTPAC%2F0047%2F2015/PT | pt_PT |
| dc.rights | openAccess | pt_PT |
| dc.subject | myocardial | pt_PT |
| dc.subject | human cardiac cell | pt_PT |
| dc.title | Towards novel stem cell and protein based therapies for myocardium regeneration | pt_PT |
| dc.title.alternative | Exploiting myocardial ischemia/reperfusion models and advanced proteomic | pt_PT |
| dc.type | doctoralThesis | pt_PT |
| thesis.degree.name | Dissertation presented to obtain the Ph.D degree in Sciences of Engineering and Technology | pt_PT |
| dc.subject.fos | Biological Engineering | pt_PT |
| Aparece nas colecções: | ITQB: CBL - PhD Theses | |
Ficheiros deste registo:
| Ficheiro | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| 2018.10_Tese_PhD_Maria_Sebastiao.pdf | 7,46 MB | Adobe PDF | Ver/Abrir |
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