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Desulfovibrio desulfuricans was the first species of a sulphatereducing
bacterium to be isolated, in 1895. Since that time, many
questions were raised in the scientific community regarding the
metabolic and ecological aspects of these bacteria. At present, there is
still a myriad of open questions remaining to be answered to enlarge our
knowledge of the metabolic pathways operative in these bacteria that
have implications in the sulfur cycle, in biocorrosion, namely in sewers
and in oil and gas systems, and in bioremediation of several toxic
metals. The work presented in this dissertation aimed at contributing
with new insights of enzymes involved in two different metabolic
systems on Desulfovibrio species, namely enzymes that play a role in the
response to oxidative stress and that are involved in the haem
biosynthetic pathway.(...)
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Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica
