Strategies for improved Adenovirus and PPR vaccine production in different cell lines:

Abstract

Viral products, including viral vaccines and viral vectors, are important tools for disease prevention and therapy. Viral vaccines, such as attenuated or inactivated rabies virus, influenza virus or hepatitis virus vaccines are powerful tools to limit the number of serious viral infections and pandemics. This type of biopharmaceuticals are used to improve human quality of life with vaccination being the most cost-effective method available for preventing economic losses and increasing the lifespan of both people and livestock. On the other hand, adenoviruses, adeno-associated viruses and retroviruses are among the viral vectors currently being developed for delivering genetic material to the target cell in a growing number of gene therapy clinical applications(...)