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Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in Portugal:
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Methicillin-resistant Staphylococcus aureus (MRSA), a human pathogen confined to hospitals (HAMRSA)
for over 30 years have been emerging worldwide in the last two decades as a leading cause
of severe infections in healthy individuals in the community (CA-MRSA). Despite its clinical
significance, in the beginning of our studies no information existed on the prevalence, and
population structure of CA-MRSA in Portugal. Moreover, it remained to be clarified how CA-MRSA
emerged in our country. In particular, it was not known if CA-MRSA emerged locally by acquisition
of the staphylococcal cassette chromosome mec (SCCmec) by established methicillin-susceptible
S. aureus (MSSA) in the community, if they were imported from abroad or have escaped from the
hospital.(...)