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Deciphering the potential of berries polyphenol metabolites for Parkinson’s Disease

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Resumo(s)

"This thesis is organized in five parts: introduction, three chapters of experimental work and a general discussion. In the introduction section, major topics necessary for a broad comprehension of this thesis is described. Major aspects about neurodegenerative diseases and (poly)phenols importance in the disease prevention are present. State of art of major cellular models used for studying (poly)phenols role in Parkinson’s disease (PD) is also described. Emphasis to the knowledge gaps of (poly)phenols potential to act inside the brain was considered such as their ability to cross and/or interact with the blood-brain barrier (BBB). Finally, a thesis rational and major work objectives are concluding the introductory section. Part of this section was included in a review published in Current Neuropharmacology.(...)"

Descrição

Palavras-chave

Parkinson´s Disease Metabolites

Contexto Educativo

Citação

Unidades organizacionais

Fascículo

Editora

Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier

Licença CC