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Orientador(es)
Resumo(s)
"This thesis is organized in five parts: introduction, three chapters of experimental work
and a general discussion.
In the introduction section, major topics necessary for a broad comprehension of this
thesis is described. Major aspects about neurodegenerative diseases and (poly)phenols
importance in the disease prevention are present. State of art of major cellular models
used for studying (poly)phenols role in Parkinson’s disease (PD) is also described.
Emphasis to the knowledge gaps of (poly)phenols potential to act inside the brain was
considered such as their ability to cross and/or interact with the blood-brain barrier
(BBB). Finally, a thesis rational and major work objectives are concluding the
introductory section. Part of this section was included in a review published in Current
Neuropharmacology.(...)"
Descrição
Palavras-chave
Parkinson´s Disease Metabolites
Contexto Educativo
Citação
Editora
Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier
